Schlag P, Meister H, Merkle P, Haferkamp O, Herfarth C
Dtsch Med Wochenschr. 1979 May 4;104(18):659-62. doi: 10.1055/s-0028-1103962.
The results of treatment of early gastric carcinoma were analysed in 65 patients. In 33 patients the operation was performed 5 years ago. The 5-year-survival rate was 70%. Prognosis was predominantly influenced by the histology of the tumour. Signet ring cell and anaplastic early carcinomas (diffuse type) had a worse prognosis than intestinal (differentiated) forms. Carcinomas localised wholly in the mucosa had no better prognosis than those penetrating into the submucosa. There is no choice of surgical method according to prognostic criteria as the diagnosis "early gastric carcinoma" can be made only postoperatively from the resection material. Bioptic proof of carcinomatous gastric mucosal changes requires full observation of the rules of cancer surgery.
对65例早期胃癌的治疗结果进行了分析。其中33例患者于5年前接受了手术。5年生存率为70%。预后主要受肿瘤组织学的影响。印戒细胞癌和间变性早期癌(弥漫型)的预后比肠型(分化型)差。完全局限于黏膜层的癌与侵犯至黏膜下层的癌相比,预后并无更好。由于“早期胃癌”的诊断只能在术后根据切除标本做出,因此无法根据预后标准选择手术方法。胃癌黏膜病变的活检确诊需要严格遵循癌症手术的规则。