Creasman W T, Rutledge F
Gynecol Oncol. 1974 Dec;2(4):482-5. doi: 10.1016/0090-8258(74)90057-2.
The extent of disease at the time of surgical exploration determines whether radical surgery can be performed in the patient who has a postirradiation cervical cancer recurrence. Contraindications to extirpative surgery includes spread of disease beyond the confines of the removable organs. This includes common iliac and periaortic lymph node metastasis. Some authors have advocated aborting the procedure when pelvic nodes are involved. In a review of 170 patients undergoing radical surgery for cervical cancer recurrence, 25 percent with positive nodes survived 5-yr compared with 36 percent with negative nodes. The finding of positive pelvic lymph nodes in itself should not be the sole reason for abandoning the operative procedure.
手术探查时疾病的范围决定了接受过放疗的宫颈癌复发患者是否能够进行根治性手术。根治性手术的禁忌证包括疾病扩散至可切除器官范围之外。这包括髂总淋巴结和腹主动脉旁淋巴结转移。一些作者主张当盆腔淋巴结受累时放弃手术。在一项对170例接受宫颈癌复发根治性手术患者的回顾性研究中,淋巴结阳性患者的5年生存率为25%,而淋巴结阴性患者为36%。盆腔淋巴结阳性这一发现本身不应成为放弃手术的唯一原因。