Resel L, Bullon A, Merchan J
Reproduccion. 1974 Jul-Sep;1(3):263-9.
Among a serie of more than 500 biopsies, the authors show some testicular lesions of difficult interpretation which do not seem to have been reported previously. The electron-microscopical findings are: Contrarily to the uniform thickening of the seminal tube's anhista basal hyalino -esclerosis, in the Klinefelter's syndrome, the anhista shows focal bizarre thickenings, which have been repeteadly observed in the 15 cases studied. Well defined collagen inside the Leydigs's cytoplasm the authors discuss the possible importance of this unique finding in a 28 years old azoospermyc as revealing cellular inmaturity (fibroblastic origin of the interstitial cells). In light microscopy, they discuss the role of the "Hiatus Germinalis", typical of the oligospermies, as related to alterations of the maturation process.
在500多例活检中，作者展示了一些难以解释的睾丸病变，这些病变似乎以前未曾有过报道。电子显微镜检查结果如下：与克莱恩费尔特综合征中精曲小管基底膜均匀增厚的透明样硬化相反，在所研究的15例病例中反复观察到，基底膜出现局灶性奇异增厚。作者在一位28岁无精子症患者的间质细胞胞质内发现了界限分明的胶原纤维，并讨论了这一独特发现可能揭示细胞不成熟（间质细胞的成纤维细胞起源）的重要性。在光学显微镜下，他们讨论了少精子症典型的“生发裂孔”与成熟过程改变的关系。
