Goldstein B D
Environ Health Perspect. 1979 Jun;30:87-9. doi: 10.1289/ehp.793087.
A study of rats acutely exposed to ozone (0.5--2.0 ppm) or nitrogen dioxide (2--20 ppm) for 2 hr and sacrificed immediately thereafter shows little similarity in the individual biochemical effects of these pollutants. No evidence of nitrogen dioxide-induced lipid peroxidation was observed. Of interest is the finding that inhalation of nitrogen dioxide increases the extent to which concanavalin A agglutinates alveolar macrophages while ozone has exactly the opposite effect.
一项对大鼠进行的研究显示,将大鼠急性暴露于臭氧(0.5 - 2.0 ppm)或二氧化氮(2 - 20 ppm)中2小时,然后立即处死,结果表明这些污染物的个体生化效应几乎没有相似之处。未观察到二氧化氮诱导脂质过氧化的证据。有趣的是,研究发现吸入二氧化氮会增加伴刀豆球蛋白A凝集肺泡巨噬细胞的程度,而臭氧则产生完全相反的效果。