Buhtz P
Zentralbl Allg Pathol. 1974;118(6):489-93.
A case of a stemcell-leukemia of a mature male macerated still-born child is described. The mother, a 20-year-old healthy bipara, a milker-maid by profession, had a normal hemogram. There was no evidence of blood group incompatibility. The autopsy of the fetus showed an excessive tumorous enlargement of the pancreas caused by the leukemic infiltration (Fig. 1). The microscopic examination of the placenta showed leukemic cells in the fetal blood vessels and the villous stroma (Fig. 2). In 1966 Werner compiled from literature 28 cases of true connatal leukemia and added a case of his own. From the newer accessible literature we collected further 19 reports (Table). In 7 of the 49 cases the connatal leukemia appeared together with Down's syndrom.
本文描述了一例成熟男性死产儿的干细胞白血病病例。母亲为20岁健康经产妇,职业是挤奶女工,血常规正常。无血型不合的证据。胎儿尸检显示胰腺因白血病浸润而出现过度的肿瘤性肿大(图1)。胎盘的显微镜检查显示胎儿血管和绒毛间质中有白血病细胞(图2)。1966年,维尔纳从文献中收集了28例真性先天性白血病病例,并补充了他自己的1例。从最新可得文献中,我们又收集到19份报告(见表)。在49例病例中的7例中,先天性白血病与唐氏综合征同时出现。