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先天性白血病和类白血病——两例细胞化学检查结果(作者译)

[Connatal leukaemia and pseudoleukaemia--two cases with cytochemical findings (author's transl)].

作者信息

Schuchmann L, Wehinger H, Möbius W, Vogt J

出版信息

Klin Padiatr. 1979 Mar;191(2):133-9.

PMID:571934
Abstract

Two newborn infants with hyperleukocytosis and blast cells in the peripheral blood are compared. Case 1 represents a connatal leukemia, which could be characterized as monocytic by the naphthol-ASesterase reaction, which was inhibited by NaF. The child died after a few hours. Case 2 must be diagnosed as "pseudoleukemia" in mongolism. The blast cells were classified as lymphoblastic on the basis of a strong granular beta-glucuronidase reaction. The patient achieved spontaneous remission.

摘要

对两名外周血中存在白细胞增多和原始细胞的新生儿进行了比较。病例1为先天性白血病,通过萘酚-AS酯酶反应可将其特征化为单核细胞性,该反应可被氟化钠抑制。患儿在数小时后死亡。病例2必须诊断为蒙古症中的“假性白血病”。根据强烈的颗粒性β-葡萄糖醛酸酶反应,将原始细胞分类为淋巴细胞性。该患者实现了自发缓解。

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Perinatal Leukaemia: a review.围产期白血病:综述
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