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樟脑抑制线粒体呼吸：放疗的一种可能辅助手段。

Mitochondrial respiration depressed by camphor: a possible aid in radiotherapy.

作者信息

Guilland-Cumming D, Smith G J

出版信息

Experientia. 1979 May 15;35(5):659. doi: 10.1007/BF01960383.

DOI:10.1007/BF01960383
PMID:446674
Abstract

Camphor has been found to decrease the rate of oxygen consumption by rat kidney mitochondria. The rate of oxygen consumption is nearly halved by the addition of 8 X 10(-3) M camphor. It is suggested that camphor may be of use in oxygenating tumours prior to radiotherapy.

摘要

已发现樟脑可降低大鼠肾线粒体的耗氧率。添加8×10⁻³M的樟脑后，耗氧率几乎减半。有人提出，樟脑在放疗前对肿瘤进行氧合方面可能有用。

相似文献

1
Mitochondrial respiration depressed by camphor: a possible aid in radiotherapy.樟脑抑制线粒体呼吸：放疗的一种可能辅助手段。
Experientia. 1979 May 15;35(5):659. doi: 10.1007/BF01960383.
2
The effect of camphor on mitochondrial respiration.樟脑对线粒体呼吸的影响。
Experientia. 1982 Feb 15;38(2):236-7. doi: 10.1007/BF01945085.
3
Inhibition of respiration by phenacetin in isolated tubules and mitochondria of rat kidney.非那西丁对大鼠肾分离肾小管及线粒体呼吸的抑制作用。
Biochem Pharmacol. 1979;28(1):57-61. doi: 10.1016/0006-2952(79)90270-3.
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In vivo parathyroid hormone status as related to respiration, phosphorylation and ion transport in rat kidney mitochondria.大鼠肾线粒体中与呼吸、磷酸化及离子转运相关的体内甲状旁腺激素状态
Endocrinology. 1966 Nov;79(5):1001-8. doi: 10.1210/endo-79-5-1001.
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Effects of indomethacin on respiration and the alpha-glycerolphosphate shuttle in rat kidney mitochondria.
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Effects of phenacetin on respiration in mitochondria isolated from rat kidney, liver and brain.非那西丁对从大鼠肾脏、肝脏和大脑分离出的线粒体呼吸作用的影响。
Biochem Pharmacol. 1979 Dec 15;28(24):3669-71. doi: 10.1016/0006-2952(79)90415-5.
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Effects of anionic xenobiotics on rat kidney. I--Tissue and mitochondrial respiration.阴离子外源性物质对大鼠肾脏的影响。I——组织和线粒体呼吸
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Post-irradiation induced sensitization of inhibition of oxidative phosphorylation by iodoacetamide.照射后碘乙酰胺诱导的氧化磷酸化抑制致敏作用。
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引用本文的文献

1
The effect of camphor on mitochondrial respiration.樟脑对线粒体呼吸的影响。
Experientia. 1982 Feb 15;38(2):236-7. doi: 10.1007/BF01945085.

本文引用的文献

1
The histological structure of some human lung cancers and the possible implications for radiotherapy.一些人类肺癌的组织学结构及其对放射治疗的可能影响。
Br J Cancer. 1955 Dec;9(4):539-49. doi: 10.1038/bjc.1955.55.
2
The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy.放疗中作为一个因素的照射时溶解在组织中的氧浓度。
Br J Radiol. 1953 Dec;26(312):638-48. doi: 10.1259/0007-1285-26-312-638.
3
Modification of radiation response through glucose-controlled respiration.
Radiat Res. 1969 Sep;39(3):623-33.
4
A metabolic control for the enhancement of radiation response.一种用于增强辐射反应的代谢控制。
Am J Roentgenol Radium Ther Nucl Med. 1970 Feb;108(2):405-11. doi: 10.2214/ajr.108.2.405.
5
An oxygen polarograph designed for undergraduate use.
Anal Biochem. 1972 Nov;50(1):206-12. doi: 10.1016/0003-2697(72)90500-3.
6
Modification of cancer cells radiosensitivity. II. Influence of the crabtree effect on radiosensitivity of Yoshida ascites sarcoma cells.
Radiobiol Radiother (Berl). 1973;14(1):73-8.
7
Radiosensitization of hypoxic cells of an in vitro tumor model by respiratory inhibitors.
Radiat Res. 1977 Feb;69(2):359-66.