Boĭko S S, Kaverina N V, Liubimov B I, Markova G A, Mitrofanov V S
Farmakol Toksikol. 1979 May-Jun;42(3):243-7.
Nonachlazine infused in the form of a solution penetrates rapidly the blood and organs. In experiments on cats it was shown that infusion of the drug into the stomach enriches the speed of blood flow and oxyhemoglobin amount in the coronary sinus blood after 2--3 minutes. Heart oxygen consumption increases slightly. Nonachlazine solution is little toxic. As a result of pharmacological research it is recommended for removing angina pectoris attacks in patients irresponsive to nitroglycerin.
以溶液形式注入的诺那氯嗪能迅速穿透血液和器官。在猫身上进行的实验表明,将该药物注入胃中后,2至3分钟内可提高冠状窦血液中的血流速度和氧合血红蛋白量。心脏耗氧量略有增加。诺那氯嗪溶液毒性很小。药理研究结果表明,它适用于治疗对硝酸甘油无反应的患者的心绞痛发作。