C3前活化剂（C3PA）作为一种急性期反应物。
C3 proactivator (C3PA) as an acute phase reactant.
作者信息
Schutte M, DiCamelli R, Murphy P, Sadove M, Gewurz H
出版信息
Clin Exp Immunol. 1974 Oct;18(2):251-6.
Abstract
C3PA levels were measured sequentially in four patients prior to and following general anaesthesia and surgery, and in twenty patients with active inflammatory diseases. Elevated levels (+70% and +60%, respectively) were observed in both patient groups, indicating that C3PA is a potent acute phase reactant. Peak levels were seen 4 days following surgery, 1–2 days after the peak of the C-reactive protein response. C3PA, along with C1s, were the complement proteins which of those tested showed the greatest elevation during the acute phase response. We conclude that the serum C3PA level should be interpreted with consideration of its role as an acute phase reactant.
摘要
在4例患者全身麻醉和手术前后以及20例患有活动性炎症性疾病的患者中，依次测量了C3PA水平。在两组患者中均观察到水平升高（分别升高70%和60%），表明C3PA是一种强效急性期反应物。术后4天出现峰值水平，在C反应蛋白反应峰值后1 - 2天出现。C3PA与C1s一样，是在急性期反应中检测到的补体蛋白中升高幅度最大的。我们得出结论，血清C3PA水平的解释应考虑其作为急性期反应物的作用。
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