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Anti-androgenicity of flutamide and its metabolite Sch 16423.

作者信息

Neri R, Peets E, Watnick A

出版信息

Biochem Soc Trans. 1979 Jun;7(3):565-9. doi: 10.1042/bst0070565.

DOI:10.1042/bst0070565
PMID:446862
Abstract
摘要

相似文献

1
Anti-androgenicity of flutamide and its metabolite Sch 16423.氟他胺及其代谢物Sch 16423的抗雄激素作用。
Biochem Soc Trans. 1979 Jun;7(3):565-9. doi: 10.1042/bst0070565.
2
Biological aspects of antiandrogens.抗雄激素的生物学特性。
J Steroid Biochem. 1975 Jun;6(6):815-9. doi: 10.1016/0022-4731(75)90309-x.
3
Flutamide inhibits testosterone-induced masculine sexual behavior in male and female rats.氟他胺抑制雄性和雌性大鼠中睾酮诱导的雄性性行为。
Endocrinology. 1980 Jun;106(6):1917-22. doi: 10.1210/endo-106-6-1917.
4
Flutamide. Mechanism of action of a new nonsteroidal antiandrogen.氟他胺。一种新型非甾体抗雄激素的作用机制。
Invest Urol. 1976 May;13(6):429-34.
5
Effects of castration, androgen replacement and flutamide treatment on the contractile function of the rat prostate.
Acta Physiol Pharmacol Latinoam. 1989;39(3):281-7.
6
Antiandrogen effects on androgen-responsive mammary tumour cells in culture.抗雄激素对培养中的雄激素反应性乳腺肿瘤细胞的作用。
J Steroid Biochem. 1981 Sep;14(9):819-22. doi: 10.1016/0022-4731(81)90227-2.
7
[Experimental anti-androgenic activity of 4-nitro-3-trifluoromethylisobutyranilide (niftholide) in rats and guinea pigs].[4-硝基-3-三氟甲基异丁酰苯胺(尼氟灭酸)在大鼠和豚鼠体内的实验性抗雄激素活性]
Farmakol Toksikol. 1977 May-Jun;40(3):336-42.
8
Pharmacology and pharmacokinetics of flutamide.氟他胺的药理学与药代动力学
Urology. 1989 Oct;34(4 Suppl):19-21; discussion 46-56. doi: 10.1016/0090-4295(89)90230-6.
9
Response of rat ventral prostate to a new and novel 5 alpha-reductase inhibitor.大鼠腹侧前列腺对一种新型5α-还原酶抑制剂的反应。
Endocrinology. 1981 Sep;109(3):830-6. doi: 10.1210/endo-109-3-830.
10
[Nucleic acid and protein biosynthesis in the accessory sex organs of rats during blockade of testosterone effect by androgen antagonist 4-nitro-3-trifluoromethylisobutyranilide].[雄激素拮抗剂4-硝基-3-三氟甲基异丁酰苯胺阻断睾酮作用期间大鼠副性器官中的核酸和蛋白质生物合成]
Probl Endokrinol (Mosk). 1978 Jan-Feb;24(1):107-11.

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Secondary Resistant Mutations to Small Molecule Inhibitors in Cancer Cells.癌细胞中对小分子抑制剂的继发性耐药突变
Cancers (Basel). 2020 Apr 9;12(4):927. doi: 10.3390/cancers12040927.
2
The impact of antiandrogen 2-hydroxyflutamide on the expression of steroidogenic enzymes in cultured porcine ovarian follicles.抗雄激素2-羟基氟他胺对培养的猪卵巢卵泡中类固醇生成酶表达的影响。
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Pharmacokinetics of Anandron in patients with advanced carcinoma of the prostate.
Cancer Chemother Pharmacol. 1988;22(1):69-76. doi: 10.1007/BF00254185.
5
Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line.雄激素抑制ZR-75-1人乳腺癌细胞系中的基础细胞增殖以及雌激素诱导的细胞增殖。
Breast Cancer Res Treat. 1988 Oct;12(2):213-25. doi: 10.1007/BF01805942.
6
The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.小鼠乳腺肿瘤病毒DNA的激素反应元件介导前病毒长末端重复序列区域转录的孕激素和雄激素诱导。
EMBO J. 1987 Feb;6(2):363-8. doi: 10.1002/j.1460-2075.1987.tb04763.x.
7
Progestin inhibition of estrogen-dependent proliferation in ZR-75-1 human breast cancer cells: antagonism by insulin.孕激素对ZR-75-1人乳腺癌细胞中雌激素依赖性增殖的抑制作用:胰岛素的拮抗作用。
Breast Cancer Res Treat. 1989 Jul;13(3):265-76. doi: 10.1007/BF02106576.
8
Multiple actions of synthetic 'progestins' on the growth of ZR-75-1 human breast cancer cells: an in vitro model for the simultaneous assay of androgen, progestin, estrogen, and glucocorticoid agonistic and antagonistic activities of steroids.合成“孕激素”对ZR-75-1人乳腺癌细胞生长的多种作用:一种用于同时检测类固醇雄激素、孕激素、雌激素和糖皮质激素激动及拮抗活性的体外模型。
Breast Cancer Res Treat. 1991 Jan-Feb;17(3):197-210. doi: 10.1007/BF01806369.