Deuschl H, Johansson S G
Clin Exp Immunol. 1974 Mar;16(3):401-12.
Quantitative measurements of immunoglobulins E, A and G were made in tracheobronchial secretion and serum of thirty-four patients in association with bronchoscopy. Measurable quantities of all three immunoglobulins were found in both secretion and serum in all patients, except in one person, in whom IgA was found neither in the secretion nor the serum, and in another person in whom no measurable IgG was found in the secretion. Calculations indicated that all immunoglobulins were produced locally in the tracheo-bronchial mucosa. This applied especially to IgA and IgE, of which 84 and 73% respectively, were calculated to have been produced locally. Quantitative differences between the three immunoglobulins were also apparent between different groups of patients. The number of patients studied is too small, however, for definite conclusions to be drawn in this respect.
在34例患者进行支气管镜检查时，对其气管支气管分泌物和血清中的免疫球蛋白E、A和G进行了定量测定。除1例患者的分泌物和血清中均未发现IgA，以及另1例患者的分泌物中未检测到可测量的IgG外，所有患者的分泌物和血清中均发现了这三种免疫球蛋白的可测量量。计算表明，所有免疫球蛋白均在气管支气管黏膜局部产生。这尤其适用于IgA和IgE，经计算分别有84%和73%是在局部产生的。不同患者组之间这三种免疫球蛋白的定量差异也很明显。然而，所研究的患者数量太少，无法在这方面得出明确结论。
