胆固醇：氧氧化还原酶对胆甾-5-烯-3β，7α-二醇的作用及标记的胆甾-4-烯-7α-醇-3-酮的酶促制备。 - Suppr | 超能文献

The action of cholesterol:oxygen oxidoreductase on cholest-5-ene-3beta, 7alpha-diol and the enzymatic preparation of the labeled cholest-4-en-7alpha-ol-3-one.

作者信息

Shimasue A

出版信息

Hiroshima J Med Sci. 1974 Dec;23(4):265-72.

Abstract

摘要

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1

The action of cholesterol:oxygen oxidoreductase on cholest-5-ene-3beta, 7alpha-diol and the enzymatic preparation of the labeled cholest-4-en-7alpha-ol-3-one.胆固醇：氧氧化还原酶对胆甾-5-烯-3β，7α-二醇的作用及标记的胆甾-4-烯-7α-醇-3-酮的酶促制备。

Hiroshima J Med Sci. 1974 Dec;23(4):265-72.

2

15-Oxygenated sterols with the unnatural cis-C-D ring junction. Studies of the metabolism of 5 alpha,14 beta-cholest-7-ene-3 beta,15 alpha-diol and 5 alpha,14 beta-cholest-7-ene-3 beta,15 beta-diol.具有非天然顺式C-D环连接的15-氧化甾醇。5α,14β-胆甾-7-烯-3β,15α-二醇和5α,14β-胆甾-7-烯-3β,15β-二醇的代谢研究。

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3

Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry.采用同位素稀释质谱法测定人血浆中的胆固醇氧化产物

Anal Biochem. 1995 Feb 10;225(1):73-80. doi: 10.1006/abio.1995.1110.

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Dietary cholesterol-oxidation products accumulate in serum and liver in apolipoprotein E-deficient mice, but do not accelerate atherosclerosis.膳食胆固醇氧化产物在载脂蛋白E缺乏小鼠的血清和肝脏中蓄积，但不会加速动脉粥样硬化。

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Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus.胆固醇氧化物作为1型和2型糖尿病氧化应激的生物标志物。

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Synthesis of polyhydroxysterols (V): efficient and stereospecific synthesis of 24-methylene-cholest-5-ene-3beta,7alpha-diol and its C-7 epimer.

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A convenient synthesis of 7 alpha-hydroxycholest-4-en-3-one by the hydroxypropyl-beta-cyclodextrin-facilitated cholesterol oxidase oxidation of 3 beta,7 alpha-cholest-5-ene-3,7-diol.通过羟丙基-β-环糊精促进胆固醇氧化酶氧化3β,7α-胆甾-5-烯-3,7-二醇方便地合成7α-羟基胆甾-4-烯-3-酮。

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Studies of the oxysterol inhibition of tumor cell growth.氧化甾醇对肿瘤细胞生长抑制作用的研究。

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Sterol synthesis. A novel reductive rearrangement of an alpha,beta-unsaturated steroidal epoxide; a new chemical synthesis of 5alpha-cholest-8(14)-en-3beta, 15alpha-diol.甾醇合成。一种新型的α,β-不饱和甾体环氧化物的还原重排反应；5α-胆甾-8(14)-烯-3β,15α-二醇的新化学合成方法。

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10

Use of an 18O2 inhalation technique and mass isotopomer distribution analysis to study oxygenation of cholesterol in rat. Evidence for in vivo formation of 7-oxo-, 7 beta-hydroxy-, 24-hydroxy-, and 25-hydroxycholesterol.使用18O2吸入技术和质量同位素异构体分布分析研究大鼠体内胆固醇的氧化。体内形成7-氧代胆固醇、7β-羟基胆固醇、24-羟基胆固醇和25-羟基胆固醇的证据。

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引用本文的文献

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Sex difference in serum 7 alpha-hydroxycholesterol levels in the rat reflect hepatic activity of 3 beta-hydroxy-delta 5-C27-steroid dehydrogenase and cholesterol 7 alpha-hydroxylase.大鼠血清7α-羟基胆固醇水平的性别差异反映了3β-羟基-δ5-C27-类固醇脱氢酶和胆固醇7α-羟化酶的肝脏活性。

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Accumulation of 7 alpha-hydroxycholesterol in liver tissue of patients with cholesterol gallstones.胆固醇性胆结石患者肝脏组织中7α-羟基胆固醇的蓄积

J Gastroenterol. 1995 Oct;30(5):651-6. doi: 10.1007/BF02367793.

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Selective reactions in the analysis and characterization of steroids by gas chromatography-mass spectrometry.气相色谱-质谱联用技术在甾体类化合物分析与表征中的选择性反应

Lipids. 1980 Sep;15(9):745-55. doi: 10.1007/BF02534028.