Azanza M F, González Barón S, Teijeira F
Rev Med Univ Navarra. 1974 Mar-Jun;18(1-2):11-23.
We have studied the cortical diffusion characteristics of seizures induced at cornu Ammonis by toppical application of:pentilenetetrazol (Metrazol), acetylcholine and stricnine. We have observed that cerebral cortex synchronise with cornu ammonis showing similar morphology, which is characteristic for the differents drugs applied. We have found similar characteristics in the cortical diffusion to those described in a previous paper 4 for the mechanical stimulation. Hence we must conclue that the variability of the discharges depends onto the position of the electrode in the anteroposterior axes. As far as the electrodes are situated backwards the activity is slower with spikes of higher amplitude and without cortical propagation.
我们已经研究了通过局部应用戊四氮（卡地阿唑）、乙酰胆碱和士的宁在海马角诱发癫痫发作的皮质扩散特征。我们观察到大脑皮质与海马角同步，呈现出相似的形态，这是所应用的不同药物的特征。我们在皮质扩散中发现了与之前一篇关于机械刺激的论文中所描述的相似特征。因此我们必须得出结论，放电的可变性取决于电极在前后轴上的位置。就电极位于后方而言，活动较慢，有更高幅度的尖峰且无皮质传播。
