Barker M C, Cobden I, Axon A T
Gut. 1979 Apr;20(4):309-11. doi: 10.1136/gut.20.4.309.
In a series of measurements of liquid-phase gastric emptying using a radionuclide marker on 35 subjects, five were identified in whom the proximal stomach and antrum were clearly distinguishable. Three of these subjects were normal controls and two suffered from systemic sclerosis. In the three normal subjects, analysis of the movement of the liquid showed the expected movement from fundus to antrum and thence through the pylorus. In the two patients with systemic sclerosis, there was, in contrast, evidence of mass retropulsion of the contents of the antrum into the fundus. In such cases, the measurement of stomach emptying based on the assumption of a single-compartment system in likely to be misleading.
在一项对35名受试者使用放射性核素标记物进行液相胃排空的系列测量中，发现有5名受试者的胃近端和胃窦清晰可辨。其中3名受试者为正常对照，2名患有系统性硬化症。在3名正常受试者中，对液体运动的分析显示了预期的从胃底到胃窦再经幽门的运动。相比之下，在2名系统性硬化症患者中，有证据表明胃窦内容物大量反流至胃底。在这种情况下，基于单室系统假设的胃排空测量可能会产生误导。
