从南美豆属植物神经叶南美豆中分离得到的具有抗肿瘤和抗菌活性的O-和C-异戊烯基取代查耳酮
[O and C prenylated chalcones with antineoplastic and antibiotic activities isolated from Lonchocarpus neuroscapha Benth].
作者信息
De Méllo J F, De Lima O G, De Albuquerque M M, Marini-Bettòlo G B, Lyra F D, Da Silva E C
出版信息
Rev Inst Antibiot (Recife). 1974 Dec;14(1-2):39-50.
In the course of our program on the antimicrobial and antineoplastic substances from higher plants we have studied many flavonoid compounds isolated from root back of Lonchocarpus neuroscapha Benth. In the present paper a slight effect on sarcoma 180 and Ehrlich carcinoma of cordoin, 4-hydroxy-cordoin and 4-hydroxy-derricin, as well as the only observed effect of derricin on sarcoma 180 were observed. The antimicrobial action of four prenylated chalcones, i.e. 4-hydroxy-derricin, 4-hydroxy-lonchocarpin, 4-hydroxy-cordoin and 4-hydroxy-isocordoin is reported.
在我们关于高等植物抗菌和抗肿瘤物质的项目过程中，我们研究了从神经叶豆（Lonchocarpus neuroscapha Benth.）根部提取的许多黄酮类化合物。在本文中，观察到柯多因、4-羟基柯多因和4-羟基德里辛对肉瘤180和艾氏癌有轻微作用，以及德里辛对肉瘤180的唯一观察到的作用。报道了四种异戊烯基化查耳酮，即4-羟基德里辛、4-羟基隆乔卡平、4-羟基柯多因和4-羟基异柯多因的抗菌作用。
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