Quero-Jiménez M, Cameron A H, Acerete F, Quero Jiménez C
Herz. 1979 Apr;4(2):161-5.
Anomalies of the atrio-ventricular valves are frequent in cases of univentricular heart with severe symptomatology during the first year of life and in necropsy material. This suggests that they are important determinants of the natural history of the malformation. Radical "corrective" surgery, in the presence of these anomalies, may be less successful than palliative programs based on sound physiological grounds. Under such circumstances, enlargement or creation of an atrial septal defect may be necessary. A careful assessment of the state of the atrio-ventricular orifices has to be included in the cardiac catheterization protocol of cases of univentricular hearts. From a morphogenetic viewpoint, a single ventricular cavity is not the appropriate substrate for two normal atrio-ventricular valves to develop.
房室瓣异常在单心室合并严重症状且于出生后第一年内发病的病例以及尸检材料中很常见。这表明它们是该畸形自然病史的重要决定因素。在存在这些异常的情况下，根治性“矫正”手术可能不如基于合理生理学依据的姑息性治疗方案成功。在这种情况下，可能需要扩大或制造房间隔缺损。对单心室病例进行心导管检查时，必须仔细评估房室口的状况。从形态发生学的角度来看，单个心室腔并非两个正常房室瓣发育的合适基础。
