Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine.

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作者信息

McPartland R P, Wang M C, Bloch A, Weinfeld H

出版信息

Cancer Res. 1974 Nov;34(11):3107-11.

PMID:4472653

Abstract

摘要

相似文献

Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine.

Cancer Res. 1974 Nov;34(11):3107-11.

The mechanism of action of 3-deazauridine in tumor cells sensitive and resistant to arabinosylcytosine.3-去氮尿苷在对阿糖胞苷敏感和耐药的肿瘤细胞中的作用机制。

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Synergistic action of 5-aza-2'-deoxycytidine and 3-deazauridine on L1210 leukemic cells and EMT6 tumor cells.5-氮杂-2'-脱氧胞苷与3-脱氮尿苷对L1210白血病细胞和EMT6肿瘤细胞的协同作用。

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Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine.5-氮杂胞苷和5,6-二氢-5-氮杂胞苷的细胞生长抑制作用及代谢的比较研究。

Cancer Res. 1977 Jul;37(7 Pt 1):1956-61.

Regulation of pyrimidine biosynthesis in cultured L1210 cells by 3-deazauridine.3-去氮尿苷对培养的L1210细胞中嘧啶生物合成的调节作用。

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Antitumor activity and biochemical effects of cyclopentenyl cytosine in mice.环戊烯基胞嘧啶对小鼠的抗肿瘤活性及生化效应

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Labelling of the thymidine and deoxycytidine bases of DNA by [2-14C]deoxycytidine in cultured L1210 cells.在培养的L1210细胞中，用[2-¹⁴C]脱氧胞苷对DNA的胸苷和脱氧胞苷碱基进行标记。

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Nucleosides and nucleotides. 158. 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)-cytosine, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)uracil, and their nucleobase analogues as new potential multifunctional antitumor nucleosides with a broad spectrum of activity.核苷与核苷酸。158. 1-(3-C-乙炔基-β-D-核糖-戊呋喃糖基)-胞嘧啶、1-(3-C-乙炔基-β-D-核糖-戊呋喃糖基)尿嘧啶及其核碱基类似物作为具有广泛活性的新型潜在多功能抗肿瘤核苷。

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J Med Chem. 1991 Jan;34(1):208-12. doi: 10.1021/jm00105a032.

Effect of 3-deazauridine on the metabolism, toxicity, and antitumor activity of azacitidine in mice bearing L1210 leukemia sensitive and resistant to cytarabine.3-去氮胞苷对携带对阿糖胞苷敏感和耐药的L1210白血病小鼠中阿扎胞苷的代谢、毒性及抗肿瘤活性的影响。

Cancer Treat Rep. 1983 Jun;67(6):547-54.

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