Fulwiler R L, Hargreaves W A, Bortman R A
Int J Addict. 1979 Feb;14(2):289-98. doi: 10.3109/10826087909060372.
Self-regulation of methadone dose during detoxification was compared to a fixed dose schedule. Self-regulators tended to maintain themselves on a stable methadone dose until forced to detoxify, but used less heroin and remained in treatment longer than the control group. The results suggest that a longer initial period of methadone stabilization may be useful in enabling addicts to detoxify successfully.
在戒毒期间,将美沙酮剂量的自我调节与固定剂量方案进行了比较。自我调节者倾向于维持稳定的美沙酮剂量,直到被迫戒毒,但与对照组相比,他们使用的海洛因较少,且接受治疗的时间更长。结果表明,较长的美沙酮初始稳定期可能有助于成瘾者成功戒毒。