Synthesis of 2'5'-oligo(A) in extracts of interferon-treated HeLa cells.

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作者信息

Minks M A, Benvin S, Maroney P A, Baglioni C

出版信息

J Biol Chem. 1979 Jun 25;254(12):5058-64.

PMID:447635

Abstract

摘要

相似文献

Synthesis of 2'5'-oligo(A) in extracts of interferon-treated HeLa cells.

J Biol Chem. 1979 Jun 25;254(12):5058-64.

2'5'Oligo(A) polymerase activity and inhibition of viral RNA synthesis in interferon-treated HeLa cells.

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Double-stranded RNA causes synthesis of 2',5'-oligo(A) and degradation of messenger RNA in interferon-treated cells.双链RNA在经干扰素处理的细胞中可引发2',5'-寡聚腺苷酸的合成及信使RNA的降解。

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Mechanism of pppA(2'p5'A)n2'p5'AOH synthesis in extracts of interferon-treated HeLa cells.干扰素处理的HeLa细胞提取物中pppA(2'p5'A)n2'p5'AOH的合成机制。

J Biol Chem. 1980 Jun 10;255(11):5031-5.

Metabolic stability of 2' 5'oligo (A) and activity of 2' 5'oligo (A)-dependent endonuclease in extracts of interferon-treated and control HeLa cells.经干扰素处理的和未处理的HeLa细胞提取物中2',5'-寡聚腺苷（2' 5'oligo (A)）的代谢稳定性及2',5'-寡聚腺苷依赖性核酸内切酶的活性

Nucleic Acids Res. 1979 Feb;6(2):767-80. doi: 10.1093/nar/6.2.767.

Chromatographic assay on DEAE-cellulose for (2'-5')-oligo(A) synthesis in cell extracts.

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Synthesis of (2'-5')oligoadenylate and activation of an endoribonuclease in interferon-treated HeLa cells infected with reovirus.呼肠孤病毒感染的经干扰素处理的HeLa细胞中(2'-5')寡腺苷酸的合成及核糖核酸内切酶的激活

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Assay of (2'-5')-oligo(A) synthesized in vitro and the analysis of naturally occurring (2'-5')-oligo(A) from intact cells.

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Heterogeneous nuclear RNA promotes synthesis of (2',5')oligoadenylate and is cleaved by the (2',5')oligoadenylate-activated endoribonuclease.不均一核RNA促进（2′，5′）寡腺苷酸的合成，并被（2′，5′）寡腺苷酸激活的核糖核酸内切酶切割。

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Maintenance of protein synthesis in spite of mRNA breakdown in interferon-treated HeLa cells infected with reovirus.在感染呼肠孤病毒的干扰素处理的HeLa细胞中，尽管mRNA降解，但蛋白质合成仍得以维持。

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