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两名松果体瘤患者的血浆褪黑素、促黄体生成素、促卵泡激素、催乳素和皮质激素水平

Plasma melatonin, luteinizing hormone, follicle-stimulating hormone, prolactin, and corticoids in two patients with pinealoma.

作者信息

Kennaway D J, McCulloch G, Matthews C D, Seamark R F

出版信息

J Clin Endocrinol Metab. 1979 Jul;49(1):144-5. doi: 10.1210/jcem-49-1-144.

DOI:10.1210/jcem-49-1-144
PMID:447812
Abstract

Plasma melatonin, LH, FSH, PRL, and corticoids were measured in two patients with pineal tumors. Plasma melatonin was not detectable (less than 7 pg/ml) in either patient while gonadotropin and cortisol levels were within the normal range. One patient exhibited low PRL levels and the other patient, a prepubertal boy, had elevated levels. The clinical value of the measurement of melatonin as a potential marker for all pineal tumors must be questioned.

摘要

对两名松果体瘤患者的血浆褪黑素、促黄体生成素(LH)、促卵泡生成素(FSH)、催乳素(PRL)和皮质类固醇进行了检测。两名患者的血浆褪黑素均检测不到(低于7 pg/ml),而促性腺激素和皮质醇水平在正常范围内。一名患者的PRL水平较低,另一名患者是青春期前男孩,其PRL水平升高。褪黑素测量作为所有松果体瘤潜在标志物的临床价值值得质疑。

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引用本文的文献

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Melatonin, Clock Genes, and Mammalian Reproduction: What Is the Link?褪黑素、生物钟基因与哺乳动物繁殖:有何联系?
Int J Mol Sci. 2021 Dec 8;22(24):13240. doi: 10.3390/ijms222413240.
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Melatonin and Female Reproduction: An Expanding Universe.褪黑素与女性生殖:一个不断扩展的领域。
Front Endocrinol (Lausanne). 2020 Mar 6;11:85. doi: 10.3389/fendo.2020.00085. eCollection 2020.
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Biomarkers of Pineal Region Tumors: A Review.松果体区肿瘤的生物标志物:综述
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Measurement of melatonin in body fluids: standards, protocols and procedures.体液中褪黑素的测量:标准、方案与程序
Childs Nerv Syst. 2011 Jun;27(6):879-91. doi: 10.1007/s00381-010-1278-8. Epub 2010 Nov 21.
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