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[Studies on the spontaneous decomposition of 4-hydroxyphosphamide and 4-hydroperoxyphosphamide by means of thin-layer chromatography].

作者信息

Völker G, Dräger U, Peter G, Hohorst H J

出版信息

Arzneimittelforschung. 1974 Aug;24(8):1172-6.

PMID:4479392
Abstract
摘要

相似文献

1
[Studies on the spontaneous decomposition of 4-hydroxyphosphamide and 4-hydroperoxyphosphamide by means of thin-layer chromatography].[利用薄层色谱法对4-羟基磷酰胺和4-氢过氧磷酰胺自发分解的研究]
Arzneimittelforschung. 1974 Aug;24(8):1172-6.
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Two stable Fenton oxidation products of cyclophosphamide (NSC-26271) as precursors of 4-hydroxycyclophosphamide (NSC-196562) under physiologic conditions.在生理条件下,环磷酰胺(NSC - 26271)的两种稳定芬顿氧化产物作为4 - 羟基环磷酰胺(NSC - 196562)的前体。
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引用本文的文献

1
Proton magnetic resonance studies of the decomposition of 4-hydroxycyclophosphamide, a microsomal metabolite of cyclophosphamide.质子磁共振研究 4-羟基环磷酰胺的分解,环磷酰胺的一种微粒体代谢物。
Pharm Res. 1984 Mar;1(2):89-92. doi: 10.1023/A:1016307515811.
2
Preclinical pharmacokinetics and stability of isophosphoramide mustard.异环磷酰胺氮芥的临床前药代动力学与稳定性
Cancer Chemother Pharmacol. 1994;33(5):391-8. doi: 10.1007/BF00686268.
3
Dithio-bis-mercaptoethanesulphonate (DIMESNA) does not prevent cellular damage by metabolites of ifosfamide and cyclophosphamide in LLC-PK1 cells.
二硫代双巯基乙烷磺酸盐(美司钠)不能预防异环磷酰胺和环磷酰胺的代谢产物对LLC-PK1细胞造成的细胞损伤。
Pediatr Nephrol. 1994 Aug;8(4):458-65. doi: 10.1007/BF00856531.
4
[Blood level and urinary excretion of activated cyclophosphamide and its deactivation products in man (author's transl)].人体内活化环磷酰胺及其失活产物的血药浓度和尿排泄情况(作者译)
J Cancer Res Clin Oncol. 1980 Jan;96(1):79-92. doi: 10.1007/BF00412899.
5
Comparative study on human pharmacokinetics of activated ifosfamide and cyclophosphamide by a modified fluorometric test.通过改良荧光测定法对活化异环磷酰胺和环磷酰胺人体药代动力学的比较研究。
J Cancer Res Clin Oncol. 1981;100(1):95-104. doi: 10.1007/BF00405906.
6
Does acrolein contribute to the cytotoxicity of cyclophosphamide?丙烯醛是否对环磷酰胺的细胞毒性有影响?
J Cancer Res Clin Oncol. 1980;98(2):119-26. doi: 10.1007/BF00405956.
7
Formation, toxicity and inactivation of acrolein during biotransformation of cyclophosphamide as studied in freshly isolated cells from rat liver and kidney.在从大鼠肝脏和肾脏新鲜分离的细胞中研究环磷酰胺生物转化过程中丙烯醛的形成、毒性及失活
Arch Toxicol. 1985 Jun;57(2):99-103. doi: 10.1007/BF00343118.
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In-vitro testing of cyclophosphamide on tumors.环磷酰胺对肿瘤的体外测试。
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9
Detection of induced tumour-resistance to cyclophosphamide by the in vitro short term test.
Arch Gynakol. 1977 Nov 29;223(4):249-57. doi: 10.1007/BF00667365.
10
Synthesis and preliminary antitumor evaluation of 4-(SR)-sulfido-cyclophosphamides.4-(SR)-硫代环磷酰胺的合成及初步抗肿瘤评价
Cancer Chemother Pharmacol. 1979;3(3):181-8. doi: 10.1007/BF00262420.