Silkworth J B, Loose L D
Adv Exp Med Biol. 1979;121(A):499-522. doi: 10.1007/978-1-4684-3593-1_43.
It is therefore proposed that: 1) environmental chemicals can have specific mechanisms of toxicity and can influence antibody-mediated immunity while having no detectable effect on cell-mediated immunity, 2) immune dysfunction is related to exposure time to a chemical and the tissue concentration of that chemical, 3) recovery of immune function may occur even though chemical exposure continues, and 4) a single assay of immune function may not be appropriate to detect chemical induced immune dysfunction.
因此，建议如下：1）环境化学物质可具有特定的毒性机制，可影响抗体介导的免疫，而对细胞介导的免疫无明显影响；2）免疫功能障碍与化学物质的暴露时间及其在组织中的浓度有关；3）即使继续接触化学物质，免疫功能也可能恢复；4）单一的免疫功能检测可能不适用于检测化学物质诱导的免疫功能障碍。
