Esato K, Oda E, Miyashita H, Yasutake S, Morita N, Yamaki R
Jpn J Surg. 1979 Jun;9(2):164-71. doi: 10.1007/BF02468852.
Twenty vascular grafts of expanded polytetrafluoroethylene with a 1.5 mm. internal diameter and a 4.0 cm. length, were placed in the femoral arteries of dogs. The animals, divided into two groups, with and without pluronic F 68, were sacrificed two weeks after surgery. The patency rate was 33.3% (2/6) and 21.5% (3/14), which was not statistically significant. One factor contributing to the occlusion of the grafts were excessive proliferation of granulation tissue due to early formation of the thrombus. Histological findings showed that the pseudointima was almost complete, although it was only about 0.114 mm. thick at the anastomotic line.
将20根内径1.5毫米、长度4.0厘米的膨体聚四氟乙烯血管移植物植入狗的股动脉。这些动物被分为两组，一组使用普朗尼克F68，另一组不使用，术后两周处死。通畅率分别为33.3%（2/6）和21.5%（3/14），无统计学意义。移植物闭塞的一个因素是血栓早期形成导致肉芽组织过度增生。组织学检查发现，假内膜几乎完整，尽管在吻合线处仅约0.114毫米厚。
