Parnas J, Flachs H, Gram L
Acta Neurol Scand. 1979 Dec;60(6):329-43. doi: 10.1111/j.1600-0404.1979.tb07659.x.
Eighteen controlled studies investigating the psychotropic effect of anti-epileptic drugs are critically reviewed. The neurochemical evidence for existence of psychotropic properties is still speculative. It seems questionable on the basis of this survey that there exist genuine psychotropic effects of antiepileptic drugs, which are not related to antiepileptic efficacy and/or differences in toxicity.
对18项研究抗癫痫药物精神作用的对照研究进行了批判性综述。关于精神作用特性存在的神经化学证据仍属推测。基于这项调查,抗癫痫药物存在与抗癫痫疗效和/或毒性差异无关的真正精神作用这一点似乎值得怀疑。