Gabuculine and isogabaculine: in vivo biochemistry and pharmacology in mice.
作者信息
Schechter P J, Tranier Y, Grove J
出版信息
Life Sci. 1979 Mar 26;24(13):1173-82. doi: 10.1016/0024-3205(79)90054-7.
PMID:449617
Abstract
摘要
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Gabuculine and isogabaculine: in vivo biochemistry and pharmacology in mice.加布可林和异加布可林：小鼠体内生物化学与药理学研究
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The in vivo inhibition of GABA-transaminase by gabaculine.加巴喷丁对体内γ-氨基丁酸转氨酶的抑制作用。
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The use of inhibitors of GABA-transaminase for the determination of GABA turnover in mouse brain regions: an evaluation of aminooxyacetic acid and gabaculine.使用γ-氨基丁酸转氨酶抑制剂测定小鼠脑区γ-氨基丁酸的周转率：对氨氧基乙酸和加巴喷丁的评估
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3-Mercaptopropionic acid: convulsant properties, effects on enzymes of the gamma-aminobutyrate system in mouse brain and antagonism by certain anticonvulsant drugs, aminooxyacetic acid and gabaculine.3-巯基丙酸：惊厥特性、对小鼠脑内γ-氨基丁酸系统酶的影响以及某些抗惊厥药物（氨氧基乙酸和加巴脲）的拮抗作用。
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The irreversible inhibition of mouse brain gamma-aminobutyric acid (GABA)-alpha-ketoglutaric acid transaminase by gabaculine.加巴喷丁对小鼠脑γ-氨基丁酸（GABA）-α-酮戊二酸转氨酶的不可逆抑制作用。
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The inactivation of gamma-aminobutyric acid transaminase in dissociated neuronal cultures from spinal cord.脊髓解离神经元培养物中γ-氨基丁酸转氨酶的失活
J Neurochem. 1981 Mar;36(3):985-90. doi: 10.1111/j.1471-4159.1981.tb01690.x.
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Attempts to correlate alterations in brain GABA metabolism by GABA-T inhibitors with their anticonvulsant effects.尝试将γ-氨基丁酸转氨酶（GABA-T）抑制剂引起的脑内γ-氨基丁酸（GABA）代谢变化与其抗惊厥作用联系起来。
Adv Exp Med Biol. 1979;123:43-57. doi: 10.1007/978-1-4899-5199-1_3.
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Drugs affecting GABA.影响γ-氨基丁酸的药物。
Prog Clin Biol Res. 1980;39:425-39.
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