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[重症监护病房中分离细菌的特性及抗生素耐药性。基于422份药敏试验结果的计算机分析研究]

[Nature and antibiotic resistance of bacteria encountered in an intensive care unit. Computerized study based on 422 antibiograms].

作者信息

du Cailar J, Griffe O, Despaux E, Gartner R, Kienlen J, Chardon P, Perez C

出版信息

Ann Anesthesiol Fr. 1979;20(6-7):633-46.

PMID:44978
Abstract

A computer analysis of 422 sheets of data from antibiograms performed on 146 patients in a resuscitation unit of multipurpose type, was performed. The study comprises the investigation of the nature of the isolated bacteria and the resistance of the organisms to antibiotics alone or in combinations. The results obtained show on the one hand, that there is a development over time of resistance to antibiotics and a change in the nature of the bacteria, and on the other, that a precise knowledge of the bacteriological data concerning a given department enables the intiation of treatment before having the antibiogram results with an increased chance of efficacy. The importance of such a study is controversial.

摘要

对一家多功能复苏病房146例患者的422份抗菌谱数据进行了计算机分析。该研究包括对分离出的细菌的性质以及这些微生物对单一抗生素或联合抗生素的耐药性进行调查。所获得的结果一方面表明,随着时间的推移,抗生素耐药性在发展,细菌的性质也在变化;另一方面表明,准确了解某一特定科室的细菌学数据能够在获得抗菌谱结果之前开始治疗,从而提高疗效。此类研究的重要性存在争议。

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