二嗪农与迟发性皮肤卟啉病
Diazinon and porphyria cutanea tarda.
作者信息
Bleakley P, Nichol A W, Collins A G
出版信息
Med J Aust. 1979 Apr 21;1(8):314-5. doi: 10.5694/j.1326-5377.1979.tb112123.x.
Abstract
Cutaneous application of diazinon to rats over a period of 12 weeks gives rise to a condition biochemically indistinguishable from porphyria cutanea tarda. Faecal porphyrin levels are elevated with the appearance of isocoproporphyrin in the faeces. Oral administration of diazinon does not appear to cause any disturbance of porphyrin metabolism.
摘要
对大鼠进行为期12周的皮肤施药，使用二嗪农，会引发一种在生物化学上与迟发性皮肤卟啉症无法区分的病症。粪便卟啉水平升高，粪便中出现异环丙卟啉。口服二嗪农似乎不会引起卟啉代谢的任何紊乱。
Zotero 插件