非随机X染色体失活——细胞选择的假象（小鼠嵌合体）
Nonrandom X-chromosome inactivation--an artifact of cell selection (mouse chimera).
作者信息
Mukherjee B B, Milet R G
出版信息
Proc Natl Acad Sci U S A. 1972 Jan;69(1):37-9. doi: 10.1073/pnas.69.1.37.
Abstract
The present study shows that a high degree of variability in the distribution of XX and XY cells exists among various tissues of artificially assembled or spontaneously occurring mouse chimeras. This variation from the expected equal distribution in various tissues of an animal may have resulted from random distribution, unequal segregation, or selective differences of such cells during development. This variation may also explain the observed intertissue and interanimal variations in the distribution of inactive paternal and maternal X-chromosomes in some mammalian females.
摘要
本研究表明，在人工组装或自然产生的小鼠嵌合体的各种组织中，XX和XY细胞的分布存在高度变异性。动物各种组织中这种与预期均等分布的差异可能是由于这些细胞在发育过程中的随机分布、不等分离或选择性差异所致。这种变异也可能解释了在一些哺乳动物雌性中观察到的非活性父本和母本X染色体在组织间和动物间分布的差异。
相似文献
1
Nonrandom X-chromosome inactivation--an artifact of cell selection (mouse chimera).非随机X染色体失活——细胞选择的假象（小鼠嵌合体）
Proc Natl Acad Sci U S A. 1972 Jan;69(1):37-9. doi: 10.1073/pnas.69.1.37.
2
Cellular distribution and possible mechanism of sex-differentiation in XX-XY chimeric mice.XX-XY嵌合小鼠性别分化的细胞分布及可能机制
Can J Genet Cytol. 1972 Dec;15(4):933-41. doi: 10.1139/g72-115.
3
Marker chromosome analysis of tetraparental AKR leads to CBA-T6 mouse chimaeras.
Differentiation. 1974 Dec;2(6):321-33. doi: 10.1111/j.1432-0436.1974.tb00367.x.
4
Marker chromosome analysis of two mouse chimaeras.两只小鼠嵌合体的标记染色体分析。
J Embryol Exp Morphol. 1975 Apr;33(2):447-57.
5
Sex-chromosome mosaicism in pouch young of marsupials Perameles and Isoodon.有袋动物袋鼬属和兔耳袋狸属育儿袋幼崽中的性染色体嵌合体。
Cytogenetics. 1971;10(2):115-20.
6
Sex chimaerism and germ cell distribution in a series of chimaeric mice.一系列嵌合小鼠中的性嵌合体和生殖细胞分布
J Embryol Exp Morphol. 1975 Feb;33(1):205-16.
7
A 39,X/40,XY/41,XYY mosaic male mouse.
Cytogenet Cell Genet. 1984;38(2):138-41. doi: 10.1159/000132046.
8
Controlling elements in the mouse. IV. Evidence of non-random X-inactivation.小鼠中的调控元件。IV. 非随机X染色体失活的证据。
Genet Res. 1981 Apr;37(2):151-60. doi: 10.1017/s0016672300020127.
9
Germ cells in XX in equilibrium XY mouse chimeras.
Basic Life Sci. 1978;12:135-42. doi: 10.1007/978-1-4684-3390-6_11.
10
引用本文的文献
1
Random X inactivation in the mule and horse placenta.马属动物胎盘的随机 X 染色体失活。
Genome Res. 2012 Oct;22(10):1855-63. doi: 10.1101/gr.138487.112. Epub 2012 May 29.
2
Polymorphism of the X-chromosome, Y-chromosome and autosomes in the Australian hopping mice, Notomys alexis, N. cervinus and N. fuscus (rodentia, muridae).
Chromosoma. 1977 May 23;61(3):243-56. doi: 10.1007/BF00292808.
3
Immunological recovery after measles.麻疹后的免疫恢复
Clin Exp Immunol. 1978 Jun;32(3):540-4.
本文引用的文献
1
SINGLE-ACTIVE-X HYPOTHESIS: CYTOLOGICAL EVIDENCE FOR RANDOM INACTIVATION OF X-CHROMOSOMES IN A FEMALE MULE COMPLEMENT.单活性X染色体假说：雌性骡细胞中X染色体随机失活的细胞学证据
Proc Natl Acad Sci U S A. 1964 Feb;51(2):252-9. doi: 10.1073/pnas.51.2.252.
2
Chromosomes of the horse, the donkey, and the mule.马、驴和骡子的染色体。
Chromosoma. 1962;13:243-8. doi: 10.1007/BF00577041.
3
Cytological identification of male and female somatic cells in the mouse.小鼠雄性和雌性体细胞的细胞学鉴定。
Exp Cell Res. 1960 Jun;20:248-9. doi: 10.1016/0014-4827(60)90251-2.
4
Mouse chimaeras developed from fused eggs.由融合卵发育而来的小鼠嵌合体。
Nature. 1961 Jun 3;190:857-60. doi: 10.1038/190857a0.
5
The murine Y chromosome as a marker.小鼠Y染色体作为一种标记物。
Transplantation. 1966 May;4(3):333-5. doi: 10.1097/00007890-196605000-00012.
6
Non-random x-inactivation in the female mule.雌性骡子中的非随机X染色体失活。
Nature. 1969 Jun 28;222(5200):1277-8. doi: 10.1038/2221277a0.
7
Is inactivation of the X chromosome in the female mule non-random?
Nature. 1970 Dec 26;228(5278):1321-2. doi: 10.1038/2281321a0.
8
Phosphoglycerate kinase polymorphism in kangaroos provides further evidence for paternal X inactivation.袋鼠中磷酸甘油酸激酶多态性为父源X染色体失活提供了进一步证据。
Nat New Biol. 1971 Mar 31;230(13):155-7. doi: 10.1038/newbio230155a0.
9
Inheritance of glucose-6-phosphate dehydrogenase variation in kangaroos.袋鼠中葡萄糖-6-磷酸脱氢酶变异的遗传
Nat New Biol. 1971 Mar 31;230(13):154-5. doi: 10.1038/newbio230154a0.
10
Cytological and biochemical correlation of late X-chromosome replication and gene inactivation in the mule.骡中晚期X染色体复制与基因失活的细胞学和生化相关性
Proc Natl Acad Sci U S A. 1971 Mar;68(3):544-8. doi: 10.1073/pnas.68.3.544.
Zotero 插件