一项比较子宫切除术、子宫切除术加阴道镭疗以及子宫镭疗加子宫切除术治疗Ⅰ期子宫内膜癌的前瞻性试验。

A prospective trail comparing hysterectomy, hysterectomy plus vaginal radium, and uterine radium plus hysterectomy in stage I endometrial carcinoma.

作者信息

Piver M S, Yazigi R, Blumenson L, Tsukada Y

出版信息

Obstet Gynecol. 1979 Jul;54(1):85-9. doi: 10.1097/00006250-197907000-00020.

DOI:10.1097/00006250-197907000-00020

Abstract

From 1958 to 1967, a prospective randomized trial was conducted in 189 women with stage I, group I endometrial adenocarcinoma, comparing treatment by hysterectomy alone, preoperative uterine radium followed by hysterectomy, and hysterectomy and postoperative vaginal radium. All women have been followed for a minimum of 10 years. The actual survival rate at 5 years for all patients was 94.5% and at 10 years, 92.6%, with no statistical significance among the 3 treatment groups. Ther was also no statistical significance in survival rate in relation to size of uterine or myometrial invasion. There was a statistically significant difference in survival between grade I and grade III lesions (P less than 0.01) and between grade II and grade III lesions (P less than 0.05).

摘要

1958年至1967年，对189例I期I组子宫内膜腺癌女性患者进行了一项前瞻性随机试验，比较单纯子宫切除术、术前子宫镭疗后行子宫切除术以及子宫切除术加术后阴道镭疗三种治疗方法。所有女性均随访至少10年。所有患者的5年实际生存率为94.5%，10年生存率为92.6%，三个治疗组之间无统计学差异。子宫大小或肌层浸润情况与生存率之间也无统计学差异。I级和III级病变之间以及II级和III级病变之间的生存率存在统计学显著差异（P<0.01）和（P<0.05）。