Baker H W, Makk L, Morrissey R W, Dickstein H
Obstet Gynecol. 1979 Aug;54(2):146-9.
To determine if preoperative irradiation should be abandoned in favor of post-hysterectomy irradiation, 65 cases of stage I endometrial carcinomas were analyzed. When no residual tumor or no myometrial invasion was found in the irradiated uterus (38 cases), a 5-year cure rate of 97.3% was obtained. When residual tumor or myometrial invasion was found, there was a 5-year cure rate of 100% in grades 1 and 2 (7 cases) but only a 20% cure rate in grade 3 lesions (5 cases). On the basis of these data there appears to be no reason to abandon preoperative irradiation in stage 1 cases. More extensive irradiation and surgery should be considered, however, in grade 3 lesions invading the myometrium.
为了确定术前放疗是否应被放弃而选择子宫切除术后放疗，对65例Ⅰ期子宫内膜癌患者进行了分析。当放疗后的子宫未发现残留肿瘤或无肌层浸润时（38例），5年治愈率为97.3%。当发现有残留肿瘤或肌层浸润时，1级和2级患者（7例）的5年治愈率为100%，但3级病变患者（5例）的治愈率仅为20%。基于这些数据，似乎没有理由在Ⅰ期病例中放弃术前放疗。然而，对于侵犯肌层的3级病变，应考虑更广泛的放疗和手术。
