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1
Rabies vaccines and interferon.狂犬病疫苗和干扰素。
J Hyg (Lond). 1972 Sep;70(3):445-53. doi: 10.1017/s0022172400063026.
2
Immune response in primates vaccinated with duck embryo cell culture rabies vaccine.用鸭胚细胞培养狂犬病疫苗接种的灵长类动物的免疫反应。
Appl Microbiol. 1973 Mar;25(3):327-31. doi: 10.1128/am.25.3.327-331.1973.
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Mediators of protection against lethal systemic vesicular stomatitis virus infection in hamsters: defective interfering particles, polyinosinate-polycytidylate, and interferon.仓鼠抵抗致死性系统性水疱性口炎病毒感染的保护介质：缺陷干扰颗粒、聚肌苷酸-聚胞苷酸和干扰素。
Infect Immun. 1982 Aug;37(2):679-86. doi: 10.1128/iai.37.2.679-686.1982.
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Rabies in rabbits and mice: protective effect of polyriboinosinic-polyribocytidylic acid.家兔和小鼠的狂犬病：聚肌苷酸-聚胞苷酸的保护作用
J Infect Dis. 1972 Apr;125(4):345-52. doi: 10.1093/infdis/125.4.345.
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Successful prophylaxis against rabies in mice and Rhesus monkeys: the interferon system and vaccine.
J Infect Dis. 1977 Aug;136(2):286-91. doi: 10.1093/infdis/136.2.286.
6
Poly(lactide-co-glycolide) microspheres: a potent oral delivery system to elicit systemic immune response against inactivated rabies virus.聚（丙交酯-乙交酯）微球：一种引发针对灭活狂犬病病毒的全身免疫反应的有效口服给药系统。
Vaccine. 2009 Mar 26;27(15):2138-43. doi: 10.1016/j.vaccine.2009.01.129. Epub 2009 Feb 6.
7
Efficacy of rabies vaccine prepared from virus grown in duck embryo.鸭胚中培养的病毒制备的狂犬病疫苗的效力
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8
Role of interferon induction in the protective activity of rabies vaccines.
J Infect Dis. 1972 Oct;126(4):408-18. doi: 10.1093/infdis/126.4.408.
9
[Pre- and post-infection rabies immunization: development of neutralizing antibodies after administration of different doses of a duck-egg vaccine in humans].
Dtsch Med Wochenschr. 1972 Dec 8;97(49):1893-8. doi: 10.1055/s-0028-1107671.
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Prophylaxis of experimental rabies with the polyriboinosinic-polyribocytidylic acid complex.
J Infect Dis. 1971 Apr;123(4):426-8. doi: 10.1093/infdis/123.4.426.

引用本文的文献

1
Editorial: Rabies vaccination in man.社论：人类狂犬病疫苗接种
Br Med J. 1974 Jan 12;1(5897):45-6.
2
The vaccination of man and other animals against rabies.人和其他动物的狂犬病疫苗接种。
Postgrad Med J. 1973 Aug;49(574):551-64. doi: 10.1136/pgmj.49.574.551.
3
Interferon response to human diploid cell strain rabies vaccines in man.人对人二倍体细胞狂犬病疫苗的干扰素反应。
Arch Virol. 1979;61(1-2):35-9. doi: 10.1007/BF01320589.

本文引用的文献

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[FIXED RABIES VIRUS AND INTERFERON].[固定狂犬病病毒与干扰素]
C R Hebd Seances Acad Sci. 1965 Jan 4;260:354-6.
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ENDOSYMBIOTIC RELATIONSHIP BETWEEN ANIMAL VIRUSES AND HOST CELLS. A STUDY OF RABIES VIRUS IN TISSUE CULTURE.动物病毒与宿主细胞之间的内共生关系。狂犬病病毒在组织培养中的研究。
J Exp Med. 1964 Dec 1;120(6):1099-116. doi: 10.1084/jem.120.6.1099.
3
CULTIVATION OF RABIES VIRUS IN HUMAN DIPLOID CELL STRAIN WI-38.狂犬病病毒在人二倍体细胞株WI-38中的培养
J Immunol. 1964 Sep;93:353-66.
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STUDIES ON THE SPECIFICITY OF INTERFERON.干扰素特异性研究
J Gen Microbiol. 1963 Dec;33:437-43. doi: 10.1099/00221287-33-3-437.
5
Body-weight and liver-SH levels of mice.小鼠的体重和肝脏巯基水平。
Nature. 1960 Apr 2;186:84-5. doi: 10.1038/186084a0.
6
Biological studies of interferon. I. Suppression of cellular infection with eastern equine encephalomyelitis virus.干扰素的生物学研究。I. 东部马脑脊髓炎病毒细胞感染的抑制
Virology. 1961 Mar;13:323-37. doi: 10.1016/0042-6822(61)90152-0.
7
Studies on chick-embryo-adapted-rabies virus. VI. Further changes in pathogenic properties following prolonged cultivation in the developing chick embryo.鸡胚适应狂犬病病毒的研究。VI. 在发育中的鸡胚中长时间培养后致病特性的进一步变化。
J Immunol. 1954 Jan;72(1):94-106.
8
Interferon production in hamsters experimentally infected with rabies virus.实验感染狂犬病病毒的仓鼠体内干扰素的产生
Proc Soc Exp Biol Med. 1966 Dec;123(3):650-4. doi: 10.3181/00379727-123-31568.
9
Autointerference of rabies virus in chick embryo fibroblasts.狂犬病病毒在鸡胚成纤维细胞中的自身干扰
Proc Soc Exp Biol Med. 1966 Nov;123(2):387-92. doi: 10.3181/00379727-123-31496.
10
Interferon as an antiviral agent in vivo: quantitative and temporal aspects of the protection of mice against Semliki Forest virus.干扰素作为体内抗病毒剂：小鼠抵抗Semliki森林病毒保护作用的定量和时间方面
Br J Exp Pathol. 1966 Aug;47(4):361-71.

狂犬病疫苗和干扰素。

Rabies vaccines and interferon.

作者信息

Turner G S

出版信息

J Hyg (Lond). 1972 Sep;70(3):445-53. doi: 10.1017/s0022172400063026.

DOI:10.1017/s0022172400063026
PMID:4506993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2130208/
Abstract

Samples of Fermi, Semple, modified Semple, Duck embryo and tissue culture rabies vaccine were inoculated by different routes and in different doses into rabbits, mice and hamsters. The vaccines induced neither detectable interferon nor immediate protection against lethal challenge with CVS rabies virus.Under similar conditions, high but transient levels of interferon were induced in control animals of the same species with the polynucleotide complex Poly I.C. Hamsters but not mice were protected by Poly I.C.-induced interferon.No autointerference by vaccine with challenge virus was established. Vaccine-induced protection in mice was directly related to immune response.

摘要

将费米疫苗、森普尔疫苗、改良森普尔疫苗、鸭胚狂犬病疫苗和组织培养狂犬病疫苗的样本，通过不同途径、以不同剂量接种到兔、小鼠和仓鼠体内。这些疫苗既未诱导出可检测到的干扰素，也未对CVS狂犬病病毒的致死性攻击产生即时保护作用。在相似条件下，用多核苷酸复合物聚肌胞（Poly I.C.）可在同一物种的对照动物中诱导出高水平但短暂的干扰素。聚肌胞诱导产生的干扰素可保护仓鼠而非小鼠。未证实疫苗对攻击病毒有自身干扰作用。疫苗在小鼠中诱导的保护作用与免疫反应直接相关。