溶液中乙酰胆碱类似物与局部麻醉剂类似物之间的构象关系。
Conformational relationships between analogs of acetylcholine and those of local anesthetics in solution.
作者信息
Makriyannis A, Sullivan R F, Mautner H G
出版信息
Proc Natl Acad Sci U S A. 1972 Nov;69(11):3416-9. doi: 10.1073/pnas.69.11.3416.
Abstract
Conformations of analogs of acetylcholine and of related local anesthetics, in which either of the oxygen atoms had been replaced by other heteroatoms, were studied in solution by nuclear magnetic resonance. Several correlations between structure and conformation could be made.
摘要
通过核磁共振对乙酰胆碱类似物以及相关局部麻醉剂的构象进行了研究，这些类似物中两个氧原子中的任何一个都已被其他杂原子取代。可以建立结构与构象之间的几种关联。
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