与血管活性肠肽片段及整个序列对应的合成肽的生物活性。
Biological activities of synthetic peptides corresponding to fragments of and to the entire sequence of the vasoactive intestinal peptide.
作者信息
Bodanszky M, Klausner Y S, Said S I
出版信息
Proc Natl Acad Sci U S A. 1973 Feb;70(2):382-4. doi: 10.1073/pnas.70.2.382.
Abstract
An octacosapeptide with the entire sequence proposed for the newly isolated vasoactive intestinal polypeptide was synthesized and had the expected biological properties. Synthetic peptides corresponding to the C-terminal hendeca-, tetradeca-, pentadeca-, and docosapeptide sequences of the vasoactive intestinal polypeptide showed activities that increased with increasing chain length.
摘要
合成了一种具有新分离的血管活性肠肽所提出的完整序列的二十八肽，它具有预期的生物学特性。与血管活性肠肽的C末端十一肽、十四肽、十五肽和二十二肽序列相对应的合成肽显示出随着链长度增加而增加的活性。
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