肿瘤性血液系统疾病中的血红蛋白异常
Hemoglobin abnormalities in neoplastic hematological disorders.
作者信息
Walker I R, Ali M A
出版信息
Can Med Assoc J. 1973 Apr 7;108(7):843-7.
Abstract
Fetal hemoglobin (F) and hemoglobin A(2) were estimated in 35 patients with malignant hematological disorders. In 9 out of 10 patients with morphological and cytochemical features of acute myeloblastic leukemia the hemoglobin F was greater than 2%. Of the other 25 patients investigated only one patient with polycythemia rubra vera had a hemoglobin F level of more than 2%. Estimation of fetal hemoglobin may be of value in the classification of acute leukemias and the increased level observed probably reflects disturbed hemoglobin synthesis in the acute myeloblastic type.
摘要
对35例恶性血液病患者进行了胎儿血红蛋白（F）和血红蛋白A2的检测。在10例具有急性髓细胞白血病形态学和细胞化学特征的患者中，有9例胎儿血红蛋白大于2%。在其他25例接受调查的患者中，只有1例真性红细胞增多症患者的胎儿血红蛋白水平超过2%。胎儿血红蛋白的检测可能对急性白血病的分类有价值，观察到的其水平升高可能反映了急性髓细胞型血红蛋白合成的紊乱。
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