• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

兔子用于甲状腺功能减退研究的适用性。

Suitability of the rabbit for hypothyroid studies.

作者信息

Holl J E, Howard L S

出版信息

Res Commun Chem Pathol Pharmacol. 1979 Jul;25(1):185-8.

PMID:451355
Abstract

New Zealand white rabbits were thyroidectomized, then examined for hypothyroidism after 6 to 8 weeks. Serum thyroxine levels were reduced 77% after surgery. This occurred without apparent calcium homeostatic imbalances even though no calcium supplementation was added to the food or water. The advantages of using the animal and procedure are discussed.

摘要

将新西兰白兔进行甲状腺切除,然后在6至8周后检查是否出现甲状腺功能减退。手术后血清甲状腺素水平降低了77%。即使在食物或水中未添加钙补充剂,也未出现明显的钙稳态失衡。文中讨论了使用该动物和手术方法的优点。

相似文献

1
Suitability of the rabbit for hypothyroid studies.兔子用于甲状腺功能减退研究的适用性。
Res Commun Chem Pathol Pharmacol. 1979 Jul;25(1):185-8.
2
A rabbit model of fatal hypothyroidism mimicking "myxedema coma" established by microscopic total thyroidectomy.通过显微全甲状腺切除术建立的模拟“黏液性水肿昏迷”的致命性甲状腺功能减退兔模型。
Endocr J. 2016 Jun 30;63(6):523-32. doi: 10.1507/endocrj.EJ16-0005. Epub 2016 Mar 26.
3
[Effect of Chinese herbs on the circadian rhythm of body temperature and heart rate in rabbits with hypothyroidism (yang deficiency)].
Zhongguo Zhong Yao Za Zhi. 1996 Apr;21(4):247-9 inside backcover.
4
Equine hypothyroidism: the long term effects of thyroidectomy on metabolism and growth in mares and stallions.马甲状腺功能减退症:甲状腺切除对母马和种马新陈代谢及生长的长期影响。
Cornell Vet. 1974 Apr;64(2):276-95.
5
Serum angiotensin-converting enzyme and plasma atrial natriuretic peptide levels in hyperthyroid and hypothyroid rabbits.甲状腺功能亢进和减退兔的血清血管紧张素转换酶及血浆心钠素水平
Jpn Heart J. 1997 Mar;38(2):273-9.
6
Thyroid hormone regulates Na(+)-Ca2+ exchanger expression during postnatal maturation and in adult rabbit ventricular myocardium.甲状腺激素在出生后成熟过程以及成年兔心室心肌中调节钠钙交换体的表达。
Cardiovasc Res. 1996 Feb;31 Spec No:E145-52.
7
Hypothyroidism enhances carbachol-induced hypothermia in the rat.甲状腺功能减退会增强大鼠体内卡巴胆碱诱导的体温过低。
Res Commun Chem Pathol Pharmacol. 1989 Jul;65(1):97-104.
8
Reciprocal interaction between seasonal testis and thyroid activity in Zembra Island wild rabbits (Oryctolagus cuniculus): effects of castration, thyroidectomy, temperature, and photoperiod.宰姆拉岛野兔(穴兔)季节性睾丸活动与甲状腺活动之间的相互作用:去势、甲状腺切除、温度和光照周期的影响
Biol Reprod. 2004 Apr;70(4):1001-9. doi: 10.1095/biolreprod.103.020008. Epub 2003 Dec 3.
9
Hypothyroidism minimizes liver damage and improves survival in rats with thioacetamide induced fulminant hepatic failure.甲状腺功能减退可减轻硫代乙酰胺诱导的暴发性肝衰竭大鼠的肝损伤并提高其生存率。
Hepatology. 1998 Apr;27(4):1013-20. doi: 10.1002/hep.510270417.
10
Treatment of primary hypothyroidism during pregnancy: is there an increase in thyroxine dose requirement in pregnancy?孕期原发性甲状腺功能减退症的治疗:孕期甲状腺素剂量需求会增加吗?
Metabolism. 2003 Jan;52(1):122-8. doi: 10.1053/meta.2003.50019.

引用本文的文献

1
Effect of hypothyroidism on the purinergic responses of corpus cavernosal smooth muscle in rabbits.甲状腺功能减退对兔阴茎海绵体平滑肌嘌呤能反应的影响。
Int Urol Nephrol. 2008;40(3):691-9. doi: 10.1007/s11255-008-9332-0. Epub 2008 Mar 8.