兔子用于甲状腺功能减退研究的适用性。
Suitability of the rabbit for hypothyroid studies.
作者信息
Holl J E, Howard L S
出版信息
Res Commun Chem Pathol Pharmacol. 1979 Jul;25(1):185-8.
PMID:451355
Abstract
New Zealand white rabbits were thyroidectomized, then examined for hypothyroidism after 6 to 8 weeks. Serum thyroxine levels were reduced 77% after surgery. This occurred without apparent calcium homeostatic imbalances even though no calcium supplementation was added to the food or water. The advantages of using the animal and procedure are discussed.
摘要
将新西兰白兔进行甲状腺切除，然后在6至8周后检查是否出现甲状腺功能减退。手术后血清甲状腺素水平降低了77%。即使在食物或水中未添加钙补充剂，也未出现明显的钙稳态失衡。文中讨论了使用该动物和手术方法的优点。
Zotero 插件