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[多灶性乳腺肿瘤问题]

[The problem of the multifocal breast neoplasm].

作者信息

Otto R, Engeler V

出版信息

Schweiz Med Wochenschr. 1979 May 19;109(20):752-7.

PMID:451500
Abstract

Nowadays, it is accepted that mammary cancer does not represent a localized tumor only, but a bilateral disease of breast tissues. During a period of 6 years, bilateral manifestations of infiltrating cancer have been observed in 12.7% of all cases. 23.2% of all breast cancer patients had a unilaterial multicentric tumor. The implications of this phenomenon with regard to control and therapy are as follows: As early diagnosis of malignant breast tumors often is possible by means of mammography, this examination should be performed regulary in high-risk patients, especially in cases of known earlier malignancy of one breast. More radical surgery should have priority, in view of the frequently observed multicentricity of breast cancers.

摘要

如今,人们公认乳腺癌并非仅仅是一种局部肿瘤,而是乳腺组织的双侧性疾病。在6年的时间里,所有病例中有12.7%观察到浸润性癌的双侧表现。所有乳腺癌患者中有23.2%患有单侧多中心肿瘤。这一现象在控制和治疗方面的影响如下:由于通过乳房X线摄影术常常能够早期诊断出恶性乳腺肿瘤,因此对于高危患者,尤其是已知一侧乳房先前有恶性肿瘤的情况,应定期进行此项检查。鉴于乳腺癌常见的多中心性,更彻底的手术应优先考虑。

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