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A new class of synthetic nucleoside analogues with broad-spectrum antiviral properties.

作者信息

Prusiner P, Sundaralingam M

出版信息

Nat New Biol. 1973 Jul 25;244(134):116-8. doi: 10.1038/newbio244116a0.

DOI:10.1038/newbio244116a0
PMID:4515918
Abstract
摘要

相似文献

1
A new class of synthetic nucleoside analogues with broad-spectrum antiviral properties.
Nat New Biol. 1973 Jul 25;244(134):116-8. doi: 10.1038/newbio244116a0.
2
Nuclear magnetic resonance studies of the solution properties of the antiviral nucleoside, 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide, the coresponding 5'-phosphate, and related triazole nucleosides.抗病毒核苷1-β-D-呋喃核糖基-1,2,4-三唑-3-甲酰胺、相应的5'-磷酸酯及相关三唑核苷溶液性质的核磁共振研究
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[Synthesis, conformation, and spectroscopy of nucleoside analogues concerning their antiviral activity].[关于核苷类似物抗病毒活性的合成、构象及光谱研究]
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Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent.新型广谱抗病毒药物1-β-D-呋喃核糖基-1,2,4-三唑-3-甲酰胺（病毒唑）的作用机制
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Heterocyclic nucleoside analogues: design and synthesis of antiviral, modified nucleosides containing isoxazole heterocycles.杂环核苷类似物：含异恶唑杂环的抗病毒修饰核苷的设计与合成
Bioorg Med Chem Lett. 2002 May 20;12(10):1395-7. doi: 10.1016/s0960-894x(02)00182-8.
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Novel 1,2,4-triazole and purine acyclic cyclopropane nucleoside analogues: synthesis, antiviral and cytostatic activity evaluations.新型1,2,4-三唑和嘌呤无环环丙烷核苷类似物：合成、抗病毒及细胞生长抑制活性评估
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Structure-activity relationships of synthetic cardiac glycosides.合成强心苷的构效关系。
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Synthesis and antiviral activities of 1,2,3-triazole functionalized thymidines: 1,3-dipolar cycloaddition for efficient regioselective diversity generation.1,2,3-三唑官能化胸苷的合成及其抗病毒活性：用于高效区域选择性多样性生成的1,3-偶极环加成反应
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Correlation between preferred sugar ring conformation and activity of nucleoside analogues against human immunodeficiency virus.核苷类似物对人免疫缺陷病毒的活性与优选糖环构象之间的相关性。
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Thiosugars. X. Novel nucleoside analogues derived from 4-thio-L-lyxofuranose.
Nucleosides Nucleotides Nucleic Acids. 2003 Oct;22(10):1867-97. doi: 10.1081/NCN-120025236.

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Activation and deactivation of a broad-spectrum antiviral drug by a single enzyme: adenosine deaminase catalyzes two consecutive deamination reactions.一种单一酶对一种广谱抗病毒药物的激活与失活作用：腺苷脱氨酶催化两个连续的脱氨反应。
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