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新生儿期短暂红细胞增多症:可能的神经系统并发症。

Transient erythrocytosis during the neonatal period: possible neurologic compications.

作者信息

Allen J P, Chilcote R

出版信息

South Med J. 1979 Jun;72(6):681-3, 686. doi: 10.1097/00007611-197906000-00014.

DOI:10.1097/00007611-197906000-00014
PMID:451651
Abstract

Transient erythrocytosis during the neonatal period may result in serious complications. Among the well recognized problems are respiratory distress, acute heart failure, and death. Little attention has been ascribed to the neurologic complications of a high hematocrit level in the neonatal period. This report describes four pediatric patients with neurologic deficits presumably due to transiently high hematocrit levels during the neonatal period. The neurologic findings in these patients were consistent with the general diagnosis of cerebral palsy. We hypothesize that they may be representative of a group of patients with seizures, structural central nervous system defects, and/or mental retardation secondary to transient erythrocytosis. Moreover, prompt recognition and treatment of this hematologic finding may prevent the immediate or late appearance of such neurologic findings.

摘要

新生儿期的短暂红细胞增多症可能会导致严重并发症。其中公认的问题有呼吸窘迫、急性心力衰竭和死亡。新生儿期高血细胞比容水平的神经并发症很少受到关注。本报告描述了4例儿科患者,其神经功能缺损可能归因于新生儿期短暂的高血细胞比容水平。这些患者的神经学表现与脑瘫的一般诊断一致。我们推测,他们可能代表了一组因短暂红细胞增多症继发癫痫、中枢神经系统结构缺陷和/或智力发育迟缓的患者。此外,及时识别和治疗这一血液学表现可能会预防此类神经学表现的即刻或晚期出现。

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引用本文的文献

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Hyperviscosity in the newborn: the scope of the problem.新生儿高黏滞血症:问题的范围
Bull N Y Acad Med. 1986 May;62(4):324-35.