[Lipid peroxidation, peroxidase activity and glutathione antiperoxide systems in rat tissues under conditions of high altitude hypoxia].

The content of lipid peroxides in rat tissues does not vary essentially under conditions of high altitude hypoxia. The peroxidase activity undergoes fluctuating changes with a significant increase in brain tissues. Among the enzymes of the glutathione antiperoxide system only the glutathione peroxidase activity shows a 5-10-fold decrease. As assumption is advanced that under conditions of hypoxia there occurs an inhibition of the glutathione antiperoxide system, which prevents the lipid peroxides level in tissues from falling.