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原发性肿瘤术前栓塞及随后肾切除术后肾细胞癌转移灶的自发消退。

Spontaneous regression of renal cell carcinoma metastases after preoperative embolization of primary tumor and subsequent nephrectomy.

作者信息

Mohr S J, Whitesel J A

出版信息

Urology. 1979 Jul;14(1):5-8. doi: 10.1016/0090-4295(79)90201-2.

DOI:10.1016/0090-4295(79)90201-2
PMID:452221
Abstract

Preoperative arterial embolization and infarction of a large renal cell carcinoma followed by radical nephrectomy seven days later led to spontaneous regression of pulmonary metastases. However, a cerebral metastatic deposit manifested itself fourteen months after surgery, requiring craniotomy. Presently, the patient is alive and well with no evidence of disease twenty-one months after his original surgery. The immunologic implications of this favorable response to treatment are discussed, and immunologic testing of similar cases is encouraged.

摘要

术前对一例大的肾细胞癌进行动脉栓塞和梗死,七天后行根治性肾切除术,随后肺转移灶自发消退。然而,术后14个月出现脑转移瘤,需要开颅手术。目前,患者在初次手术后21个月仍存活且状况良好,无疾病迹象。讨论了这种对治疗的良好反应的免疫学意义,并鼓励对类似病例进行免疫学检测。

相似文献

1
Spontaneous regression of renal cell carcinoma metastases after preoperative embolization of primary tumor and subsequent nephrectomy.原发性肿瘤术前栓塞及随后肾切除术后肾细胞癌转移灶的自发消退。
Urology. 1979 Jul;14(1):5-8. doi: 10.1016/0090-4295(79)90201-2.
2
Complete regression of multiple pulmonary metastases in a patient with advanced renal cell carcinoma treated by occlusion of the renal artery with subsequent radical nephrectomy and progesterone.一名晚期肾细胞癌患者,通过肾动脉闭塞,随后进行根治性肾切除术及使用黄体酮治疗后,其多处肺转移灶完全消退。
Eur Urol. 1983;9(4):254-6. doi: 10.1159/000474095.
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The role of preoperative embolization in renal cell carcinoma.术前栓塞在肾细胞癌中的作用。
J Urol. 1984 Apr;131(4):641-6. doi: 10.1016/s0022-5347(17)50556-x.
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Regression of Metastases after Nephrectomy for Renal Cell Carcinoma.
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[A case of renal adenocarcinoma with spontaneously regressing pulmonary metastases].[一例伴有自发性消退肺转移的肾腺癌病例]
J Urol Nephrol (Paris). 1971 Mar;77(3):225-34.
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The role of embolization and nephrectomy in the treatment of metastatic renal carcinoma.栓塞和肾切除术在转移性肾癌治疗中的作用。
Urol Clin North Am. 1980 Oct;7(3):719-30.
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Spontaneous regression of pulmonary metastases after nephrectomy for renal cell carcinoma.
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Spontaneous regression of a pulmonary metastasis after nephrectomy for renal cell carcinoma.
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引用本文的文献

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Combinations of Anti-Angiogenic Agents and Immune Checkpoint Inhibitors in Renal Cell Carcinoma: Best Option?抗血管生成药物与免疫检查点抑制剂联合用于肾细胞癌:最佳选择?
Cancers (Basel). 2023 Feb 7;15(4):1048. doi: 10.3390/cancers15041048.
2
Tumour devascularisation as a potential immunotherapeutic strategy.肿瘤血管生成阻断作为一种潜在的免疫治疗策略。
Oncoimmunology. 2018 Oct 11;8(1):e1526614. doi: 10.1080/2162402X.2018.1526614. eCollection 2019.
3
Embolizing techniques in urology.泌尿外科中的栓塞技术。
J R Soc Med. 1984 Nov;77(11):909-10. doi: 10.1177/014107688407701102.
4
Arterial embolization in patients with renal carcinoma.
Int Urol Nephrol. 1989;21(6):575-8. doi: 10.1007/BF02559612.