Kaisary A V, Williams G, Riddle P R
J Urol. 1984 Apr;131(4):641-6. doi: 10.1016/s0022-5347(17)50556-x.
A prospective study was done to assess the effect of embolization on the technical ease of nephrectomy, change in the immunological status of the patient and subsequent behavior of tumors and/or metastases in 55 patients with renal cell carcinoma. We found that embolization makes the operation easier technically. No changes in responses to delayed hypersensitivity skin tests were found after embolization with or without nephrectomy. There may be a response following embolization and adjuvant radical nephrectomy in some patients with limited lung metastases. No significant regression of renal cell carcinoma and/or metastases after embolization alone or with nephrectomy and hormonal/chemotherapeutic treatment was demonstrated. Survival of patients with metastatic renal cell carcinoma was longer for those who underwent embolization and nephrectomy than for those who underwent embolization alone.
对55例肾细胞癌患者进行了一项前瞻性研究，以评估栓塞对肾切除术技术操作的便利性、患者免疫状态的变化以及肿瘤和/或转移灶后续行为的影响。我们发现，栓塞在技术上使手术更容易。无论是否进行肾切除术，栓塞后迟发型超敏皮肤试验的反应均无变化。一些肺转移受限的患者在栓塞及辅助性根治性肾切除术后可能会有反应。单独栓塞或栓塞联合肾切除术及激素/化疗治疗后，肾细胞癌和/或转移灶均未出现明显消退。转移性肾细胞癌患者中，接受栓塞及肾切除术的患者比仅接受栓塞的患者生存期更长。
