[一种介导多种磷脂从脂质体转运至线粒体的大鼠肝细胞提取物蛋白质的特性]
[Characteristics of a rat liver cellular extract protein which mediates transport of various phospholipids from liposomes to mitochondria].
作者信息
Ruggiero F M, Megli F M, Landriscina C
出版信息
Boll Soc Ital Biol Sper. 1979 Feb 15;55(3):183-9.
PMID:45244
Abstract
The effect of pH, Ca++ and Na+ concentration on the phosphatidylethanolamine transport from liposomes to mitochondria by an aspecific soluble rat liver protein has been studied. Results obtained indicate that at pH higher than 6.5 and Ca++ ion concentrations from 5 mM on the transport is strongly inhibited. Preliminary data with ESR spectrometry concerning the nature of lipoprotein association between phosphatidylethanolamine and carrier protein during the transport are also presented.
摘要
研究了pH值、钙离子（Ca++）和钠离子（Na+）浓度对一种非特异性可溶性大鼠肝脏蛋白介导的磷脂酰乙醇胺从脂质体转运至线粒体的影响。所得结果表明，在pH值高于6.5且钙离子浓度从5 mM起，转运受到强烈抑制。还给出了利用电子自旋共振光谱法（ESR）获得的关于转运过程中磷脂酰乙醇胺与载体蛋白之间脂蛋白结合性质的初步数据。
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