关于单乙烯基d-尿胆素的存在。
On the existence of a mono-vinyl d-urobilin.
作者信息
Chedekel M, Bovey F A, Brewster A I, Petryka Z J, Weimer M, Watson C J, Moscowitz A, Lightner D A
出版信息
Proc Natl Acad Sci U S A. 1974 May;71(5):1599-601. doi: 10.1073/pnas.71.5.1599.
Abstract
Chromic acid degradation of a d-urobilin, obtained after incubation of bilirubin in fecal bacterial cultures, gave methylvinylmaleimide and methylethylmaleimide. The d-urobilin, molecular weight 588, C(33)H(40)-N(4)O(6), clearly showed the presence of both vinyl and ethyl resonances in the nuclear magnetic resonance spectrum. These results point unambiguously to a urobilin structure with one vinyl and one ethyl beta-substituent.
摘要
在粪便细菌培养物中胆红素孵育后获得的d-尿胆素经铬酸降解，产生甲基乙烯基马来酰亚胺和甲基乙基马来酰亚胺。分子量为588、化学式为C(33)H(40)-N(4)O(6)的d-尿胆素在核磁共振谱中清楚地显示出乙烯基和乙基共振峰的存在。这些结果明确指向一种具有一个乙烯基和一个乙基β-取代基的尿胆素结构。
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本文引用的文献
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The effect of aureomycin on urobilinogen formation and the fecal flora.金霉素对尿胆原形成及粪便菌群的影响。
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Bilirubin and urobilins in germfree, ex-germfree, and conventional rats.无菌、曾经无菌及普通大鼠体内的胆红素和尿胆素
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The isolation of crystalline d-urobilinogen.结晶性d-尿胆原的分离。
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A further study of crystalline d-urobilin.结晶d-尿胆素的进一步研究。
J Biol Chem. 1956 Feb;218(2):633-9.
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Mass spectrometry and ferric chloride oxidation applied to urobilinoid structures.应用于尿胆素原类结构的质谱分析和氯化铁氧化法。
Arch Biochem Biophys. 1969 May;131(2):566-76. doi: 10.1016/0003-9861(69)90431-7.
7
[Degradation of bile pigments with chromic acid and chromate].[胆汁色素用铬酸和铬酸盐的降解]
Hoppe Seylers Z Physiol Chem. 1969 Nov;350(11):1291-300.
8
Gold from dross: the first century of the urobilinoids.从糟粕中提炼黄金：尿胆素类物质的首个百年
Ann Intern Med. 1969 Apr;70(4):839-51. doi: 10.7326/0003-4819-70-4-839.
9
Structure of d-urobilin.d-尿胆素的结构。
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