Linzenmeier G, Haralambie E, Dermoumi H
Zentralbl Bakteriol Orig A. 1979 Apr;243(2-3):326-35.
The methods of quantitative analysis of aerobe and anaerobe microbes and fungi stool specimens are described. The results of the studies in health people are compared to the results in patients undergoing surgical treatment of intestinal tract. A group of these patients received Neomycin and Bacitracin orally as short-time chemoprophylaxis to diminish possible woundinfection and/or sepsis. After oral medication germs as Bifidobacterium, Bacteroides and Clostridium (not Cl. perfringens) are reduced or lost, Veillonella, Eubacterium, Fusiformis, Peptostreptococcus and Lactobacillus were suppressed. Resistant strains of E. coli and Enterococci increased to high concentration/g faeces. After treatment the rate of gram-negative bacteria resistant to Neomycin increased. This might be of epidemiologically importance for the distribution of microbes resistant to Neomycin and other aminoglycosides as Klebsiella, Candida spec. and Torulopsis.
描述了对需氧菌、厌氧菌和真菌粪便标本进行定量分析的方法。将健康人的研究结果与接受肠道手术治疗的患者的结果进行了比较。其中一组患者口服新霉素和杆菌肽作为短期化学预防措施，以减少可能的伤口感染和/或败血症。口服药物后，双歧杆菌、拟杆菌和梭菌（非产气荚膜梭菌）数量减少或消失，韦荣球菌、真杆菌、梭形杆菌、消化链球菌和乳酸杆菌受到抑制。大肠杆菌和肠球菌的耐药菌株浓度增加至高浓度/克粪便。治疗后，对新霉素耐药的革兰氏阴性菌比例增加。这可能在新霉素和其他氨基糖苷类耐药微生物（如克雷伯菌、念珠菌属和球拟酵母菌）的传播方面具有流行病学意义。
