测定个体小鼠消化道的定植抗性。
Determination of the colonization resistance of the digestive tract of individual mice.
作者信息
van der Waaij D, Berghuis J M
出版信息
J Hyg (Lond). 1974 Jun;72(3):379-87. doi: 10.1017/s0022172400023615.
Abstract
It has been shown that it is possible to investigate the colonization resistance in individual mice by determining the concentration of a certain contaminant (S.R.-E. coli) in the faeces during the first 4 days after contamination. Experimental contamination is contra-indicated in many cases such as in individuals with decreased resistance to infection. Particularly in this group, the value of the colonization resistance should be determined. It appeared to be possible to determine the colonization resistance in such individuals by quantitative biotyping of the Enterobacteriaceae species in the faeces on several consecutive days.
摘要
已经表明，在污染后的头4天内，通过测定粪便中某种污染物（S.R.-大肠杆菌）的浓度来研究个体小鼠的定植抗力是可行的。在许多情况下，如对感染抵抗力降低的个体，实验性污染是禁忌的。特别是在这一组中，应该确定定植抗力的值。通过连续几天对粪便中肠杆菌科菌种进行定量生物分型，似乎有可能确定这类个体的定植抗力。
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