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母亲白血病接受6-巯基嘌呤治疗后的新生儿并发症。

A neonatal complication of maternal leukaemia treated with 6-mercaptopurine.

作者信息

McConnell J B, Bhoola R

出版信息

Postgrad Med J. 1973 Mar;49(569):211-3. doi: 10.1136/pgmj.49.569.211.

DOI:10.1136/pgmj.49.569.211
PMID:4528388
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2495383/
Abstract

A 24-year-old African mother, who had received 6-mercaptopurine for acute leukaemia from before conception and throughout her pregnancy is described. The child, born prematurely, was anaemic at birth, with many features of a micro-angiopathic haemolytic anaemia. It is suggested that the mother's disease or treatment was involved in the aetiology of this anaemia.

摘要

本文描述了一位24岁的非洲母亲，她在受孕前及整个孕期因急性白血病接受了6-巯基嘌呤治疗。该名早产婴儿出生时贫血，具有许多微血管病性溶血性贫血的特征。提示母亲的疾病或治疗与该贫血的病因有关。

相似文献

1
A neonatal complication of maternal leukaemia treated with 6-mercaptopurine.母亲白血病接受6-巯基嘌呤治疗后的新生儿并发症。
Postgrad Med J. 1973 Mar;49(569):211-3. doi: 10.1136/pgmj.49.569.211.
2
[Current problems of iron deficiency in pregnant women, fetuses and newborn infants].[孕妇、胎儿及新生儿缺铁的当前问题]
Akush Ginekol (Mosk). 1983 Jun(6):3-6.
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本文引用的文献

1
The effect of 6-mercaptopurine on the rat fetus and on reproduction of the rat.6-巯基嘌呤对大鼠胎儿及大鼠生殖的影响。
Ann N Y Acad Sci. 1954 Dec 6;60(2):220-7. doi: 10.1111/j.1749-6632.1954.tb40012.x.
2
PASSAGE OF LEUKEMIC CELLS ACROSS THE PLACENTA.白血病细胞穿过胎盘
N Engl J Med. 1964 Jul 16;271:124-7. doi: 10.1056/NEJM196407162710304.
3
Acute leukemia and pregnancy.急性白血病与妊娠
Ann Intern Med. 1960 Oct;53:656-71. doi: 10.7326/0003-4819-53-4-656.
4
Acute granulocytic leukemia in pregnancy: report of four cases, with apparent acceleration by prednisone in one.妊娠期急性粒细胞白血病：4例报告，其中1例病情明显因泼尼松而加速进展。
Am J Med Sci. 1959 Feb;237(2):194-204. doi: 10.1097/00000441-195902000-00007.
5
Pregnancy in acute leukaemia treated with 6-mercaptopurine.
Lancet. 1956 Dec 15;271(6955):1268-9. doi: 10.1016/s0140-6736(56)90039-3.
6
Acute leukemia in pregnancy.
Am J Obstet Gynecol. 1966 Oct 1;96(3):316-20. doi: 10.1016/0002-9378(66)90232-8.