脑膜瘤的DNA含量
DNA content of meningiomas.
作者信息
Frederiksen P, Reske-Nielsen E, Bichel P
出版信息
Acta Neuropathol. 1979 Apr 12;46(1-2):65-8. doi: 10.1007/BF00684806.
PMID:452863
Abstract
Flow cytometric DNA analysis was carried out in 35 meningiomas. Thirty-three had diploid stem lines while two were aneuploid having a triploid DNA mode. Both aneuploid meningiomas were grossly huge nodular tumours and one had malignant histologic features. Flow cytometry in meningiomas is a rapid means of determining the DNA modes and adds objective information to microscopy. Appropriate cases may be selected for further cytogenetic studies.
摘要
对35例脑膜瘤进行了流式细胞术DNA分析。其中33例具有二倍体干细胞系，而2例为非整倍体，其DNA模式为三倍体。这两例非整倍体脑膜瘤在大体上均为巨大的结节状肿瘤，其中1例具有恶性组织学特征。脑膜瘤的流式细胞术是确定DNA模式的快速方法，可为显微镜检查提供客观信息。可选择合适的病例进行进一步的细胞遗传学研究。
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