L细胞DNA的长嘧啶序列：定位于重复DNA
Long pyrimidine tracts of L-cell DNA: localization to repeated DNA.
作者信息
Straus N A, Birnboim H C
出版信息
Proc Natl Acad Sci U S A. 1974 Aug;71(8):2992-5. doi: 10.1073/pnas.71.8.2992.
Abstract
Like HeLa DNA, L-cell DNA contains a significant number of unexpectedly long pyrimidine tracts. 1.3% of the thymidine residues of L-cell DNA are found in these long polypyrimidine tracts. Analysis of L-cell DNA fractions with different rates of reassociation indicates that polypyrimidine tracts are associated with "repeated" DNA. Longer pyrimidine tracts appear to have a higher repetition frequency than shorter tracts, and some may be repeated as many as 5 x 10(4) times in L-cell DNA.
摘要
与海拉细胞DNA一样，L细胞DNA含有大量出乎意料的长嘧啶序列。L细胞DNA中1.3%的胸腺嘧啶残基存在于这些长的多嘧啶序列中。对具有不同复性速率的L细胞DNA组分进行分析表明，多嘧啶序列与“重复”DNA相关。较长的嘧啶序列似乎比较短的序列具有更高的重复频率，并且在L细胞DNA中有些序列可能重复多达5×10⁴次。
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