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本文引用的文献

1
SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA.DNA大小与形状的沉降研究
J Mol Biol. 1965 Feb;11:373-90. doi: 10.1016/s0022-2836(65)80064-x.
2
Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.DNA中的重复序列。数以十万计的DNA序列拷贝已被纳入高等生物的基因组中。
Science. 1968 Aug 9;161(3841):529-40. doi: 10.1126/science.161.3841.529.
3
Analysis of long pyrimidine polynucleotides in HeLa cell nuclear DNA: absence of polydeoxythymidylate.对HeLa细胞核DNA中长嘧啶多核苷酸的分析:无聚脱氧胸苷酸。
Proc Natl Acad Sci U S A. 1973 Aug;70(8):2189-92. doi: 10.1073/pnas.70.8.2189.

L细胞DNA的长嘧啶序列:定位于重复DNA

Long pyrimidine tracts of L-cell DNA: localization to repeated DNA.

作者信息

Straus N A, Birnboim H C

出版信息

Proc Natl Acad Sci U S A. 1974 Aug;71(8):2992-5. doi: 10.1073/pnas.71.8.2992.

DOI:10.1073/pnas.71.8.2992
PMID:4528633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC388605/
Abstract

Like HeLa DNA, L-cell DNA contains a significant number of unexpectedly long pyrimidine tracts. 1.3% of the thymidine residues of L-cell DNA are found in these long polypyrimidine tracts. Analysis of L-cell DNA fractions with different rates of reassociation indicates that polypyrimidine tracts are associated with "repeated" DNA. Longer pyrimidine tracts appear to have a higher repetition frequency than shorter tracts, and some may be repeated as many as 5 x 10(4) times in L-cell DNA.

摘要

与海拉细胞DNA一样,L细胞DNA含有大量出乎意料的长嘧啶序列。L细胞DNA中1.3%的胸腺嘧啶残基存在于这些长的多嘧啶序列中。对具有不同复性速率的L细胞DNA组分进行分析表明,多嘧啶序列与“重复”DNA相关。较长的嘧啶序列似乎比较短的序列具有更高的重复频率,并且在L细胞DNA中有些序列可能重复多达5×10⁴次。