Sonobe H, Fujioka I, Nakatoh S, Miyake K, Taguchi K, Motoi M, Ogawa K
Acta Pathol Jpn. 1979 May;29(3):479-84. doi: 10.1111/j.1440-1827.1979.tb00203.x.
A case of a 46-year-old Japanese male having fibrosarcoma of bone is reported. The tumor developed in the proximal metaphysis of the left femur. During the three years following onset of the disease with symptoms of local pain and mass, the patient was operated on three times (curettage and bone graft, curettage and bone graft with Jwett's nail fixation and disarticulation). The tumor was found to be an intraosseous translucent lesion on x-ray examiation. Histologically, the tumor consisted of compact or loose, atypical spindle cells, producing abundant collagen-fibers without any osteoid, bony or cartilage formation. From the clinical and pathological findings, this case is thought to be a typical central fibrosarcoma of bone.
报告了一例46岁日本男性患骨纤维肉瘤的病例。肿瘤发生在左股骨近端干骺端。在疾病出现局部疼痛和肿块症状后的三年里，患者接受了三次手术（刮除术和骨移植、刮除术和骨移植并使用朱厄特钉固定以及关节离断术）。X线检查发现肿瘤为骨内半透明病变。组织学上，肿瘤由致密或疏松的非典型梭形细胞组成，产生大量胶原纤维，无任何类骨质、骨或软骨形成。根据临床和病理结果，该病例被认为是典型的骨中心纤维肉瘤。
