Ishikawa K, Yanagisawa A, Ishihara T, Tamura T, Inoue M
Am Heart J. 1979 Jul;98(1):73-82. doi: 10.1016/0002-8703(79)90322-3.
Sequential changes of orthogonal electrocardiograms in 70 patients with progressive dystrophy of the Duchenne type (PMD) were investigated. The patients were classified into eight stages from the mildest, S(1), to the severest, S(8), according to Swinyard-Deaver's criteria. The most prominent finding was a progressive reduction in R wave amplitude in Lead X (Rx) with advancing severity. It was considered that loss of electrical activity in the left ventricular free wall might be mainly responsible for the reduction in the Rx amplitude. An abnormal Q wave was frequently observed in each stage. Its occurrence remained essentially unchanged with the progression of PMD. Thus, the presence of a deep Q wave cannot serve as an index for assessing the heart involvement, but rather, we conclude that a reduction of the Rx amplitude can be a useful criterion for estimating the extent of cardiac involvement in PMD.
对70例杜兴型进行性肌营养不良症（PMD）患者的正交心电图的连续变化进行了研究。根据斯温亚德 - 迪弗标准，将患者从最轻度的S(1)到最重度的S(8)分为八个阶段。最显著的发现是随着病情加重，X导联（Rx）的R波振幅逐渐降低。认为左心室游离壁电活动丧失可能是Rx振幅降低的主要原因。在每个阶段都经常观察到异常Q波。随着PMD的进展，其出现情况基本保持不变。因此，深Q波的存在不能作为评估心脏受累的指标，相反，我们得出结论，Rx振幅降低可作为估计PMD心脏受累程度的有用标准。
